Alaska
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly <5 (†) 0 (0.0) <5 (†) 0 (0.0) <5 (†) 18 (1.9)
Anophthalmia / microphthalmia 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Anotia / microtia 13 (5.0) <5 (†) <5 (†) 6 (13.8) 6 (5.9) 60 (6.2)
Aortic valve stenosis 5 (1.9) 0 (0.0) <5 (†) <5 (†) <5 (†) 22 (2.3)
Atrial septal defect 461 (178.0) 39 (211.2) 83 (210.2) 90 (206.7) 393 (387.4) 2258 (233.4)
Atrioventricular septal defect (endocardial cushion defect) 14 (5.4) <5 (†) <5 (†) <5 (†) <5 (†) 50 (5.2)
Biliary atresia <5 (†) <5 (†) <5 (†) <5 (†) 12 (11.8) 46 (4.8)
Bladder exstrophy 0 (0.0) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) <5 (†)
Choanal atresia 7 (2.7) <5 (†) <5 (†) <5 (†) <5 (†) 28 (2.9)
Cleft lip alone (without cleft palate) 7 (2.7) 0 (0.0) <5 (†) 0 (0.0) 7 (6.9) 30 (3.1)
Cleft lip with cleft palate 10 (3.9) 0 (0.0) <5 (†) <5 (†) 13 (12.8) 58 (6.0)
Cleft palate alone (without cleft lip) 18 (7.0) <5 (†) <5 (†) <5 (†) 20 (19.7) 94 (9.7)
Cloacal exstrophy <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†)
Clubfoot 21 (8.1) <5 (†) <5 (†) 5 (11.5) 8 (7.9) 82 (8.5)
Coarctation of aorta 9 (3.5) 0 (0.0) <5 (†) <5 (†) 5 (4.9) 40 (4.1)
Common truncus (truncus arteriosus or TA) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Congenital cataract 15 (5.8) <5 (†) <5 (†) <5 (†) <5 (†) 58 (6.0)
Congenital posterior urethral valves 6 (4.5) 0 (0.0) <5 (†) 0 (0.0) <5 (†) 22 (4.4) 1
Craniosynostosis 29 (11.2) <5 (†) 5 (12.7) <5 (†) 15 (14.8) 110 (11.4)
Deletion 22q11.2 <5 (†) 0 (0.0) 0 (0.0) <5 (†) <5 (†) 14 (1.4)
Diaphragmatic hernia <5 (†) 0 (0.0) <5 (†) <5 (†) 7 (6.9) 30 (3.1)
Double outlet right ventricle (DORV) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Ebstein anomaly <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†) 10 (1.0)
Encephalocele 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Esophageal atresia / tracheoesophageal fistula 9 (3.5) <5 (†) <5 (†) <5 (†) <5 (†) 38 (3.9)
Gastroschisis 6 (2.3) <5 (†) <5 (†) <5 (†) 11 (10.8) 62 (6.4)
Holoprosencephaly <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†) 12 (1.2)
Hypoplastic left heart syndrome <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†)
Hypospadias 124 (92.6) 8 (87.4) 9 (45.5) 13 (56.6) 29 (55.9) 382 (76.7) 1
Interrupted aortic arch (IAA) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Limb deficiencies (reduction defects) 8 (3.1) <5 (†) <5 (†) <5 (†) 8 (7.9) 52 (5.4)
Omphalocele 29 (11.2) 10 (54.1) <5 (†) 8 (18.4) 25 (24.6) 152 (15.7)
Pulmonary valve atresia and stenosis 22 (8.5) <5 (†) <5 (†) <5 (†) 29 (28.6) 130 (13.4)
Pulmonary valve atresia 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Rectal and large intestinal atresia / stenosis 11 (4.2) 0 (0.0) <5 (†) <5 (†) 16 (15.8) 72 (7.4)
Renal agenesis / hypoplasia 25 (9.7) 5 (27.1) 7 (17.7) <5 (†) 8 (7.9) 98 (10.1)
Single ventricle 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Small intestinal atresia / stenosis 6 (2.3) <5 (†) <5 (†) <5 (†) 15 (14.8) 64 (6.6)
Spina bifida without anencephaly 5 (1.9) 0 (0.0) 0 (0.0) <5 (†) <5 (†) 20 (2.1)
Tetralogy of Fallot (TOF) 5 (1.9) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†) 20 (2.1)
Total anomalous pulmonary venous connection (TAPVC) <5 (†) 0 (0.0) <5 (†) <5 (†) <5 (†) 14 (1.4)
Transposition of the great arteries (TGA) <5 (†) 0 (0.0) <5 (†) <5 (†) <5 (†) 12 (1.2)
Dextro-Transposition of great arteries (d-TGA) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Tricuspid valve atresia and stenosis 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Tricuspid valve atresia 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Trisomy 13 <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†)
Trisomy 18 <5 (†) <5 (†) 0 (0.0) <5 (†) 0 (0.0) 10 (1.0)
Trisomy 21 (Down syndrome) 34 (13.1) <5 (†) 5 (12.7) 8 (18.4) 10 (9.9) 130 (13.4)
Turner syndrome <5 (†) 0 (0.0) <5 (†) 5 (24.3) <5 (†) 22 (4.7) 2
Ventricular septal defect 219 (84.6) 9 (48.7) 24 (60.8) 25 (57.4) 191 (188.3) 990 (102.3)
Total live births 25896 1847 3948 4354 10145 96752 3
Male Live Births 13391 915 1979 2295 5186 49788
Female Live Births 12505 932 1969 2059 4959 46964
Notes
1- Data for this condition include male and unknown gender cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown gender cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown gender.

General comments
†Counts <5 and associated prevalences are suppressed
*Data for totals include unknown/other
§Data for all conditions may include cases where the year of delivery was unknown. When year of delivery was unknown year of last known prenatal test was used as a proxy.