| Department of Defense Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||||||
| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
|||
| Anencephaly | 17 (0.5) | <5 (†) | 13 (1.7) | <5 (†) | 0 (0.0) | 36 (0.7) | |
| Anophthalmia / microphthalmia | 47 (1.5) | 10 (1.3) | 15 (1.9) | <5 (†) | 0 (0.0) | 75 (1.4) | |
| Anotia / microtia | 100 (3.2) | 16 (2.1) | 29 (3.7) | 7 (2.5) | <5 (†) | 167 (3.2) | |
| Aortic valve stenosis | 119 (3.8) | 9 (1.2) | 25 (3.2) | <5 (†) | <5 (†) | 162 (3.1) | |
| Atrial septal defect | 5726 (182.3) | 1441 (191.9) | 1326 (169.2) | 464 (166.4) | 120 (172.7) | 9422 (180.1) | |
| Atrioventricular septal defect (endocardial cushion defect) | 213 (6.8) | 42 (5.6) | 46 (5.9) | 22 (7.9) | <5 (†) | 337 (6.4) | |
| Biliary atresia | 87 (2.8) | 37 (4.9) | 31 (4.0) | 16 (5.7) | <5 (†) | 178 (3.4) | |
| Bladder exstrophy | <5 (†) | <5 (†) | <5 (†) | <5 (†) | <5 (†) | 10 (0.2) | |
| Choanal atresia | 89 (2.8) | 16 (2.1) | 17 (2.2) | 5 (1.8) | <5 (†) | 135 (2.6) | |
| Cleft lip alone (without cleft palate) | 209 (6.7) | 17 (2.3) | 35 (4.5) | 23 (8.2) | 7 (10.1) | 301 (5.8) | |
| Cleft lip with cleft palate | 214 (6.8) | 21 (2.8) | 49 (6.3) | 26 (9.3) | 6 (8.6) | 327 (6.3) | |
| Cleft palate alone (without cleft lip) | 352 (11.2) | 53 (7.1) | 73 (9.3) | 34 (12.2) | 10 (14.4) | 535 (10.2) | |
| Cloacal exstrophy | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | <5 (†) | |
| Clubfoot | 907 (28.9) | 186 (24.8) | 210 (26.8) | 58 (20.8) | 15 (21.6) | 1432 (27.4) | |
| Coarctation of aorta | 288 (9.2) | 69 (9.2) | 61 (7.8) | 19 (6.8) | 10 (14.4) | 463 (8.9) | |
| Congenital cataract | 103 (3.3) | 28 (3.7) | 27 (3.4) | 5 (1.8) | <5 (†) | 177 (3.4) | |
| Congenital posterior urethral valves | 46 (2.8) | 19 (5.0) | 14 (3.5) | <5 (†) | 0 (0.0) | 82 (3.1) | 1 |
| Craniosynostosis | 1106 (35.2) | 169 (22.5) | 265 (33.8) | 94 (33.7) | 22 (31.7) | 1706 (32.6) | |
| Deletion 22q11.2 | 42 (1.3) | 6 (0.8) | 8 (1.0) | <5 (†) | 0 (0.0) | 62 (1.2) | |
| Diaphragmatic hernia | 114 (3.6) | 31 (4.1) | 26 (3.3) | 13 (4.7) | 5 (7.2) | 196 (3.7) | |
| Double outlet right ventricle (DORV) | 91 (2.9) | 30 (4.0) | 24 (3.1) | 14 (5.0) | <5 (†) | 169 (3.2) | |
| Ebstein anomaly | 35 (1.1) | 5 (0.7) | 9 (1.1) | <5 (†) | <5 (†) | 57 (1.1) | |
| Encephalocele | 34 (1.1) | 13 (1.7) | 9 (1.1) | <5 (†) | 0 (0.0) | 63 (1.2) | |
| Esophageal atresia / tracheoesophageal fistula | 94 (3.0) | 19 (2.5) | 22 (2.8) | 5 (1.8) | <5 (†) | 145 (2.8) | |
| Gastroschisis | 125 (4.0) | 32 (4.3) | 45 (5.7) | 8 (2.9) | 5 (7.2) | 221 (4.2) | |
| Holoprosencephaly | 27 (0.9) | 9 (1.2) | 5 (0.6) | <5 (†) | 0 (0.0) | 44 (0.8) | |
| Hypoplastic left heart syndrome | 131 (4.2) | 26 (3.5) | 31 (4.0) | 9 (3.2) | <5 (†) | 211 (4.0) | |
| Hypospadias | 1997 (123.7) | 416 (108.9) | 337 (84.4) | 128 (88.8) | 28 (79.0) | 3020 (112.7) | 1 |
| Interrupted aortic arch (IAA) | 38 (1.2) | <5 (†) | 10 (1.3) | <5 (†) | <5 (†) | 56 (1.1) | |
| Limb deficiencies (reduction defects) | 167 (5.3) | 45 (6.0) | 37 (4.7) | 8 (2.9) | 0 (0.0) | 262 (5.0) | |
| Omphalocele | 58 (1.8) | 18 (2.4) | 14 (1.8) | 7 (2.5) | 0 (0.0) | 100 (1.9) | |
| Rectal and large intestinal atresia / stenosis | 152 (4.8) | 43 (5.7) | 49 (6.3) | 18 (6.5) | 6 (8.6) | 278 (5.3) | |
| Renal agenesis / hypoplasia | 264 (8.4) | 68 (9.1) | 59 (7.5) | 19 (6.8) | 8 (11.5) | 437 (8.4) | |
| Single ventricle | 86 (2.7) | 11 (1.5) | 21 (2.7) | 6 (2.2) | <5 (†) | 128 (2.4) | |
| Small intestinal atresia / stenosis | 135 (4.3) | 40 (5.3) | 35 (4.5) | 14 (5.0) | <5 (†) | 229 (4.4) | |
| Spina bifida without anencephaly | 122 (3.9) | 16 (2.1) | 36 (4.6) | <5 (†) | <5 (†) | 190 (3.6) | |
| Total anomalous pulmonary venous connection (TAPVC) | 54 (1.7) | 6 (0.8) | 14 (1.8) | 0 (0.0) | <5 (†) | 78 (1.5) | |
| Trisomy 13 | 32 (1.0) | 16 (2.1) | 6 (0.8) | 6 (2.2) | 0 (0.0) | 60 (1.1) | |
| Trisomy 18 | 59 (1.9) | 17 (2.3) | 12 (1.5) | 8 (2.9) | 0 (0.0) | 98 (1.9) | |
| Trisomy 21 (Down syndrome) | 442 (14.1) | 101 (13.4) | 109 (13.9) | 38 (13.6) | 11 (15.8) | 718 (13.7) | |
| Turner syndrome | 63 (4.1) | 9 (2.4) | 13 (3.4) | 6 (4.5) | 0 (0.0) | 92 (3.6) | 2 |
| Ventricular septal defect | 2579 (82.1) | 530 (70.6) | 613 (78.2) | 190 (68.1) | 65 (93.5) | 4122 (78.8) | |
| Total live births | 314173 | 75103 | 78348 | 27882 | 6949 | 523081 | 3 |
| Male Live Births | 161440 | 38216 | 39922 | 14418 | 3545 | 268042 | |
| Female Live Births | 152733 | 36887 | 38426 | 13464 | 3404 | 255039 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence of posterior urethral valve is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
|||||||
| Department of Defense Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 193 (4.5) | 5 (0.7) | 221 (4.2) |
| Trisomy 13 | 34 (0.8) | 22 (3.1) | 60 (1.1) |
| Trisomy 18 | 61 (1.4) | 34 (4.8) | 98 (1.9) |
| Trisomy 21 (Down syndrome) | 412 (9.5) | 276 (38.8) | 718 (13.7) |
| Total live births | 431623 | 71097 | 523081 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
|||
| Department of Defense Notes on Specific Birth Defects |
|
| Defect | Site Comment |
|---|---|
| Anencephaly | The DoD Birth and Infant Health Research (BIHR) program only captures livebirths |
| Spina bifida without anencephaly | The BIHR program only captures livebirths |
| Ventricular septal defect | All ICD-10-CM coded cases that meet the BIHR program case criteria are included. The BIHR program relies on ICD-10-CM codes and cannot distinguish CDC/BPA codes 745.487 or 745.498 |
| Atrial septal defect | The BIHR program relies on ICD-10-CM codes and cannot differentiate PFO |
| Atrioventricular septal defect (endocardial cushion defect) | The BIHR program relies on ICD-10-CM codes and cannot distinguish CDC/BPA code 745.487 |
| Tricuspid valve atresia and stenosis | The BIHR program relies on ICD-10-CM codes. Cases with tricuspid stenosis or hypoplasia are included |
| Omphalocele | Criteria for an omphalocele case: One diagnosis from inpatient records during the first month of life |
| Trisomy 13 | The BIHR program only captures livebirths |
| Trisomy 21 (Down syndrome) | The BIHR program only captures livebirths |
| Trisomy 18 | The BIHR program only captures livebirths |