| Iowa Birth Defects Counts and Prevalence 2018-2021 (Prevalence per 10,000 Live Births) |
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| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
|||
| Anencephaly | 5 (0.4) | 0 (0.0) | <5 (†) | 0 (0.0) | 0 (0.0) | 42 (2.8) | |
| Anophthalmia / microphthalmia | 14 (1.2) | <5 (†) | <5 (†) | 0 (0.0) | <5 (†) | 23 (1.6) | |
| Anotia / microtia | 24 (2.1) | 0 (0.0) | 6 (4.0) | <5 (†) | <5 (†) | 35 (2.4) | |
| Aortic valve stenosis | 27 (2.4) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 31 (2.1) | |
| Atrial septal defect | 216 (19.0) | 29 (27.2) | 38 (25.4) | 16 (28.6) | <5 (†) | 314 (21.2) | |
| Atrioventricular septal defect (endocardial cushion defect) | 74 (6.5) | <5 (†) | 10 (6.7) | 0 (0.0) | <5 (†) | 93 (6.3) | |
| Biliary atresia | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 5 (0.3) | |
| Bladder exstrophy | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 0 (0.0) | <5 (†) | |
| Choanal atresia | 8 (0.7) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 9 (0.6) | |
| Cleft lip alone (without cleft palate) | 47 (4.1) | <5 (†) | 5 (3.3) | <5 (†) | 0 (0.0) | 57 (3.8) | |
| Cleft lip with cleft palate | 56 (4.9) | <5 (†) | 12 (8.0) | <5 (†) | <5 (†) | 90 (6.1) | |
| Cleft palate alone (without cleft lip) | 84 (7.4) | 6 (5.6) | 9 (6.0) | <5 (†) | <5 (†) | 107 (7.2) | |
| Cloacal exstrophy | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
| Clubfoot | 213 (18.7) | 14 (13.1) | 19 (12.7) | 6 (10.7) | <5 (†) | 283 (19.1) | |
| Coarctation of aorta | 80 (7.0) | 5 (4.7) | 11 (7.4) | <5 (†) | <5 (†) | 101 (6.8) | |
| Common truncus (truncus arteriosus or TA) | 5 (0.4) | 0 (0.0) | <5 (†) | 0 (0.0) | 0 (0.0) | 11 (0.7) | |
| Congenital cataract | 36 (3.2) | <5 (†) | 7 (4.7) | <5 (†) | 0 (0.0) | 49 (3.3) | |
| Congenital posterior urethral valves | 12 (2.1) | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 17 (2.2) | 1 |
| Craniosynostosis | 83 (7.3) | 0 (0.0) | 8 (5.3) | <5 (†) | <5 (†) | 96 (6.5) | |
| Deletion 22q11.2 | 25 (2.2) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 29 (2.0) | |
| Dextro-Transposition of great arteries (d-TGA) | 22 (1.9) | 0 (0.0) | <5 (†) | <5 (†) | <5 (†) | 28 (1.9) | |
| Diaphragmatic hernia | 42 (3.7) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 56 (3.8) | |
| Double outlet right ventricle (DORV) | 21 (1.8) | 5 (4.7) | <5 (†) | 0 (0.0) | 0 (0.0) | 39 (2.6) | |
| Ebstein anomaly | 9 (0.8) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 12 (0.8) | |
| Encephalocele | 7 (0.6) | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 20 (1.3) | |
| Esophageal atresia / tracheoesophageal fistula | 28 (2.5) | 6 (5.6) | 5 (3.3) | 0 (0.0) | 0 (0.0) | 41 (2.8) | |
| Gastroschisis | 33 (2.9) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 42 (2.8) | |
| Holoprosencephaly | 12 (1.1) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 35 (2.4) | |
| Hypoplastic left heart syndrome | 18 (1.6) | <5 (†) | 5 (3.3) | <5 (†) | 0 (0.0) | 32 (2.2) | |
| Hypospadias | 375 (64.4) | 21 (38.8) | 26 (34.2) | 5 (17.5) | <5 (†) | 431 (56.9) | 1 |
| Interrupted aortic arch (IAA) | 7 (0.6) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 10 (0.7) | |
| Limb deficiencies (reduction defects) | 42 (3.7) | <5 (†) | 8 (5.3) | <5 (†) | 0 (0.0) | 75 (5.1) | |
| Omphalocele | 15 (1.3) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 40 (2.7) | |
| Pulmonary valve atresia | 11 (1.0) | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 15 (1.0) | |
| Pulmonary valve atresia and stenosis | 105 (9.2) | 11 (10.3) | 9 (6.0) | 8 (14.3) | 0 (0.0) | 135 (9.1) | |
| Rectal and large intestinal atresia / stenosis | 33 (2.9) | 5 (4.7) | <5 (†) | 5 (8.9) | 0 (0.0) | 49 (3.3) | |
| Renal agenesis / hypoplasia | 63 (5.5) | 5 (4.7) | 9 (6.0) | 6 (10.7) | 0 (0.0) | 96 (6.5) | |
| Single ventricle | 5 (0.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 8 (0.5) | |
| Small intestinal atresia / stenosis | 31 (2.7) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 37 (2.5) | |
| Spina bifida without anencephaly | 39 (3.4) | <5 (†) | <5 (†) | <5 (†) | <5 (†) | 57 (3.8) | |
| Tetralogy of Fallot (TOF) | 44 (3.9) | 8 (7.5) | <5 (†) | <5 (†) | 0 (0.0) | 61 (4.1) | |
| Total anomalous pulmonary venous connection (TAPVC) | 16 (1.4) | 0 (0.0) | <5 (†) | <5 (†) | <5 (†) | 21 (1.4) | |
| Transposition of the great arteries (TGA) | 28 (2.5) | 0 (0.0) | <5 (†) | <5 (†) | <5 (†) | 36 (2.4) | |
| Tricuspid valve atresia | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 7 (0.5) | |
| Tricuspid valve atresia and stenosis | 22 (1.9) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 36 (2.4) | |
| Trisomy 13 | 8 (0.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 21 (1.4) | |
| Trisomy 18 | 16 (1.4) | <5 (†) | <5 (†) | 0 (0.0) | <5 (†) | 54 (3.6) | |
| Trisomy 21 (Down syndrome) | 155 (13.6) | 13 (12.2) | 30 (20.1) | 5 (8.9) | <5 (†) | 242 (16.3) | |
| Turner syndrome | 11 (2.0) | 0 (0.0) | <5 (†) | 0 (0.0) | 0 (0.0) | 30 (4.1) | 2 |
| Ventricular septal defect | 551 (48.4) | 49 (46.0) | 79 (52.8) | 23 (41.1) | 5 (86.8) | 738 (49.8) | |
| Total live births | 113754 | 10654 | 14958 | 5594 | 576 | 148174 | 3 |
| Male Live Births | 58202 | 5419 | 7592 | 2857 | 280 | 75727 | |
| Female Live Births | 55551 | 5235 | 7365 | 2737 | 296 | 72445 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
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| Iowa Birth Defects Counts and Prevalence 2018-2021 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 41 (3.2) | <5 (†) | 42 (2.8) |
| Trisomy 13 | 16 (1.3) | 5 (2.3) | 21 (1.4) |
| Trisomy 18 | 22 (1.7) | 32 (15.0) | 54 (3.6) |
| Trisomy 21 (Down syndrome) | 126 (9.9) | 116 (54.2) | 242 (16.3) |
| Total live births | 126673 | 21403 | 148174 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
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| Iowa Notes on Specific Birth Defects |
|
| Defect | Site Comment |
|---|---|
| Ventricular septal defect | Data for this condition exclude Inlet VSD |
| Cleft palate alone (without cleft lip) | In determining Cleft palate alone, code 749.080 (bifid uvula) is excluded. |
| Choanal atresia | Data for this condition exclude choanal stenosis. |
| Universal comment | Table 1b and Table 2b Total male live births and Total female live births do not match Total live births because there are 2 unknown sex case |
| Universal comment | IA uses CDC/BPA codes. |
| Universal comment | Data for all conditions exclude probable/possible cases. |
| Limb deficiencies (reduction defects) | Data for this condition exclude other specified and unspecified limb reductions. |