| Illinois Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
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| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
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| Anencephaly | 49 (1.4) | 13 (1.2) | 16 (1.1) | <5 (†) | 0 (0.0) | 81 (1.2) | |
| Anophthalmia / microphthalmia | 70 (1.9) | 27 (2.5) | 30 (2.0) | <5 (†) | 0 (0.0) | 131 (1.9) | |
| Anotia / microtia | 69 (1.9) | 16 (1.5) | 52 (3.5) | 10 (2.3) | 0 (0.0) | 147 (2.2) | |
| Aortic valve stenosis | 114 (3.2) | 23 (2.1) | 47 (3.2) | 7 (1.6) | 0 (0.0) | 192 (2.8) | |
| Atrial septal defect | 1441 (39.8) | 583 (53.1) | 565 (38.3) | 170 (39.0) | 5 (119.0) | 2767 (40.8) | |
| Atrioventricular septal defect (endocardial cushion defect) | 238 (6.6) | 95 (8.6) | 106 (7.2) | 24 (5.5) | 0 (0.0) | 468 (6.9) | |
| Biliary atresia | 22 (0.6) | 8 (0.7) | 7 (0.5) | <5 (†) | 0 (0.0) | 40 (0.6) | |
| Bladder exstrophy | <5 (†) | 6 (0.5) | <5 (†) | 0 (0.0) | 0 (0.0) | 14 (0.2) | |
| Choanal atresia | 56 (1.5) | 21 (1.9) | 27 (1.8) | 0 (0.0) | 0 (0.0) | 104 (1.5) | |
| Cleft lip alone (without cleft palate) | 127 (3.5) | 33 (3.0) | 37 (2.5) | 12 (2.8) | 0 (0.0) | 210 (3.1) | |
| Cleft lip with cleft palate | 247 (6.8) | 54 (4.9) | 102 (6.9) | 20 (4.6) | <5 (†) | 428 (6.3) | |
| Cleft palate alone (without cleft lip) | 226 (6.2) | 54 (4.9) | 76 (5.2) | 14 (3.2) | <5 (†) | 372 (5.5) | |
| Cloacal exstrophy | 14 (0.4) | 10 (0.9) | 6 (0.4) | <5 (†) | 0 (0.0) | 32 (0.5) | |
| Clubfoot | 602 (16.6) | 189 (17.2) | 202 (13.7) | 52 (11.9) | 5 (119.0) | 1055 (15.5) | |
| Coarctation of aorta | 247 (6.8) | 51 (4.6) | 85 (5.8) | 17 (3.9) | <5 (†) | 402 (5.9) | |
| Common truncus (truncus arteriosus or TA) | 29 (0.8) | 9 (0.8) | 7 (0.5) | <5 (†) | 0 (0.0) | 47 (0.7) | |
| Congenital cataract | 39 (1.1) | 22 (2.0) | 15 (1.0) | 5 (1.1) | <5 (†) | 82 (1.2) | |
| Congenital posterior urethral valves | 34 (1.8) | 28 (5.0) | 9 (1.2) | 5 (2.2) | 0 (0.0) | 76 (2.2) | 1 |
| Craniosynostosis | 178 (4.9) | 21 (1.9) | 69 (4.7) | 12 (2.8) | 0 (0.0) | 280 (4.1) | |
| Deletion 22q11.2 | 51 (1.4) | 19 (1.7) | 12 (0.8) | <5 (†) | 0 (0.0) | 84 (1.2) | |
| Dextro-Transposition of great arteries (d-TGA) | 123 (3.4) | 33 (3.0) | 40 (2.7) | 9 (2.1) | 0 (0.0) | 205 (3.0) | |
| Diaphragmatic hernia | 115 (3.2) | 32 (2.9) | 38 (2.6) | 16 (3.7) | 0 (0.0) | 203 (3.0) | |
| Double outlet right ventricle (DORV) | 61 (1.7) | 35 (3.2) | 41 (2.8) | 10 (2.3) | 0 (0.0) | 148 (2.2) | |
| Ebstein anomaly | 39 (1.1) | 6 (0.5) | 15 (1.0) | <5 (†) | 0 (0.0) | 64 (0.9) | |
| Encephalocele | 34 (0.9) | 17 (1.5) | 13 (0.9) | <5 (†) | <5 (†) | 69 (1.0) | |
| Esophageal atresia / tracheoesophageal fistula | 108 (3.0) | 25 (2.3) | 29 (2.0) | 8 (1.8) | 0 (0.0) | 170 (2.5) | |
| Gastroschisis | 118 (3.3) | 41 (3.7) | 55 (3.7) | 8 (1.8) | 0 (0.0) | 225 (3.3) | |
| Holoprosencephaly | 37 (1.0) | 22 (2.0) | 18 (1.2) | 6 (1.4) | 0 (0.0) | 85 (1.3) | |
| Hypoplastic left heart syndrome | 109 (3.0) | 44 (4.0) | 44 (3.0) | 9 (2.1) | 0 (0.0) | 210 (3.1) | |
| Hypospadias | 1500 (80.8) | 416 (74.2) | 289 (38.7) | 158 (70.2) | 6 (295.6) | 2371 (68.2) | 1 |
| Interrupted aortic arch (IAA) | 26 (0.7) | 10 (0.9) | 11 (0.7) | <5 (†) | 0 (0.0) | 49 (0.7) | |
| Limb deficiencies (reduction defects) | 170 (4.7) | 91 (8.3) | 50 (3.4) | 11 (2.5) | <5 (†) | 326 (4.8) | |
| Omphalocele | 80 (2.2) | 30 (2.7) | 31 (2.1) | 11 (2.5) | 0 (0.0) | 154 (2.3) | |
| Pulmonary valve atresia | 25 (0.7) | 17 (1.5) | 15 (1.0) | <5 (†) | 0 (0.0) | 59 (0.9) | |
| Pulmonary valve atresia and stenosis | 285 (7.9) | 124 (11.3) | 137 (9.3) | 29 (6.7) | <5 (†) | 577 (8.5) | |
| Rectal and large intestinal atresia / stenosis | 184 (5.1) | 67 (6.1) | 75 (5.1) | 25 (5.7) | <5 (†) | 355 (5.2) | |
| Renal agenesis / hypoplasia | 379 (10.5) | 147 (13.4) | 148 (10.0) | 33 (7.6) | <5 (†) | 711 (10.5) | |
| Single ventricle | 33 (0.9) | 12 (1.1) | 12 (0.8) | <5 (†) | 0 (0.0) | 60 (0.9) | |
| Small intestinal atresia / stenosis | 123 (3.4) | 49 (4.5) | 65 (4.4) | 13 (3.0) | 0 (0.0) | 252 (3.7) | |
| Spina bifida without anencephaly | 121 (3.3) | 36 (3.3) | 60 (4.1) | 7 (1.6) | <5 (†) | 230 (3.4) | |
| Tetralogy of Fallot (TOF) | 192 (5.3) | 68 (6.2) | 70 (4.8) | 21 (4.8) | <5 (†) | 353 (5.2) | |
| Total anomalous pulmonary venous connection (TAPVC) | 39 (1.1) | 14 (1.3) | 26 (1.8) | 11 (2.5) | 0 (0.0) | 90 (1.3) | |
| Transposition of the great arteries (TGA) | 138 (3.8) | 36 (3.3) | 44 (3.0) | 14 (3.2) | 0 (0.0) | 232 (3.4) | |
| Tricuspid valve atresia | 22 (0.6) | 9 (0.8) | 7 (0.5) | <5 (†) | 0 (0.0) | 39 (0.6) | |
| Tricuspid valve atresia and stenosis | 46 (1.3) | 31 (2.8) | 21 (1.4) | <5 (†) | 0 (0.0) | 100 (1.5) | |
| Trisomy 13 | 33 (0.9) | 19 (1.7) | 18 (1.2) | 5 (1.1) | <5 (†) | 77 (1.1) | |
| Trisomy 18 | 79 (2.2) | 35 (3.2) | 45 (3.1) | 10 (2.3) | <5 (†) | 175 (2.6) | |
| Trisomy 21 (Down syndrome) | 512 (14.2) | 129 (11.7) | 306 (20.8) | 55 (12.6) | <5 (†) | 1008 (14.8) | |
| Turner syndrome | 50 (2.8) | 20 (3.7) | 17 (2.3) | 9 (4.3) | 0 (0.0) | 97 (2.9) | 2 |
| Ventricular septal defect | 2102 (58.1) | 602 (54.8) | 990 (67.2) | 237 (54.4) | 10 (238.1) | 3952 (58.2) | |
| Total live births | 361643 | 109860 | 147359 | 43556 | 420 | 678991 | 3 |
| Male Live Births | 185708 | 56044 | 74705 | 22512 | 203 | 347462 | |
| Female Live Births | 175928 | 53812 | 72651 | 21043 | 217 | 331513 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
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| Illinois Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 218 (4.1) | 7 (0.5) | 225 (3.3) |
| Trisomy 13 | 50 (0.9) | 27 (1.8) | 77 (1.1) |
| Trisomy 18 | 59 (1.1) | 116 (7.6) | 175 (2.6) |
| Trisomy 21 (Down syndrome) | 460 (8.7) | 548 (36.0) | 1008 (14.8) |
| Total live births | 526731 | 152246 | 678991 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
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| Illinois Notes on Specific Birth Defects |
|
| Defect | Site Comment |
|---|---|
| Ventricular septal defect | Data exclude probable cases and inlet ventricular septal defects (VSDs), including common atrioventricular canal type VSD. |
| Atrioventricular septal defect (endocardial cushion defect) | Data inlcude inlet ventricular septal defects (VSDs) including common atrioventricluar canal type VSD. |
| Universal comment | Data for all conditions include live births to age 2, and fetal deaths (these include stillbirths of 20 weeks gestation or more and miscarriages where families chose to hold funerals). |