| Indiana Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||||||
| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
|||
| Anencephaly | 24 (0.8) | 5 (1.0) | 6 (2.1) | <5 (†) | 0 (0.0) | 37 (0.9) | |
| Anophthalmia / microphthalmia | 21 (0.7) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 29 (0.7) | |
| Anotia / microtia | 56 (1.9) | 8 (1.7) | 13 (4.6) | <5 (†) | <5 (†) | 84 (2.1) | |
| Aortic valve stenosis | 46 (1.5) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 53 (1.3) | |
| Atrial septal defect | 1224 (41.2) | 247 (50.9) | 121 (42.6) | 47 (43.0) | 0 (0.0) | 1660 (42.2) | |
| Atrioventricular septal defect (endocardial cushion defect) | 143 (4.8) | 24 (5.0) | 12 (4.2) | <5 (†) | 0 (0.0) | 184 (4.7) | |
| Biliary atresia | 17 (0.6) | 6 (1.2) | <5 (†) | <5 (†) | 0 (0.0) | 30 (0.8) | |
| Bladder exstrophy | 13 (0.4) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 15 (0.4) | |
| Choanal atresia | 33 (1.1) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 39 (1.0) | |
| Cleft lip alone (without cleft palate) | 113 (3.8) | 11 (2.3) | 9 (3.2) | <5 (†) | <5 (†) | 140 (3.6) | |
| Cleft lip with cleft palate | 198 (6.7) | 19 (3.9) | 25 (8.8) | 6 (5.5) | <5 (†) | 253 (6.4) | |
| Cleft palate alone (without cleft lip) | 281 (9.5) | 17 (3.5) | 18 (6.3) | <5 (†) | <5 (†) | 322 (8.2) | |
| Cloacal exstrophy | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | <5 (†) | |
| Clubfoot | 350 (11.8) | 61 (12.6) | 28 (9.9) | 10 (9.2) | 0 (0.0) | 454 (11.5) | |
| Coarctation of aorta | 170 (5.7) | 25 (5.2) | 19 (6.7) | 5 (4.6) | 0 (0.0) | 219 (5.6) | |
| Common truncus (truncus arteriosus or TA) | 18 (0.6) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 22 (0.6) | |
| Congenital cataract | 34 (1.1) | <5 (†) | 6 (2.1) | <5 (†) | 0 (0.0) | 47 (1.2) | |
| Congenital posterior urethral valves | 40 (2.6) | 7 (2.8) | 5 (3.4) | 5 (8.8) | 0 (0.0) | 58 (2.9) | 1 |
| Craniosynostosis | 218 (7.3) | 17 (3.5) | 15 (5.3) | 9 (8.2) | <5 (†) | 264 (6.7) | |
| Deletion 22q11.2 | 36 (1.2) | 5 (1.0) | <5 (†) | <5 (†) | 0 (0.0) | 48 (1.2) | |
| Dextro-Transposition of great arteries (d-TGA) | 77 (2.6) | <5 (†) | 6 (2.1) | <5 (†) | 0 (0.0) | 90 (2.3) | |
| Diaphragmatic hernia | 99 (3.3) | 18 (3.7) | 12 (4.2) | <5 (†) | 0 (0.0) | 135 (3.4) | |
| Double outlet right ventricle (DORV) | 91 (3.1) | 19 (3.9) | 10 (3.5) | 0 (0.0) | 0 (0.0) | 120 (3.1) | |
| Ebstein anomaly | 25 (0.8) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 32 (0.8) | |
| Encephalocele | 26 (0.9) | 7 (1.4) | 6 (2.1) | 0 (0.0) | 0 (0.0) | 39 (1.0) | |
| Esophageal atresia / tracheoesophageal fistula | 84 (2.8) | 13 (2.7) | <5 (†) | <5 (†) | 0 (0.0) | 106 (2.7) | |
| Gastroschisis | 116 (3.9) | 11 (2.3) | 18 (6.3) | <5 (†) | 0 (0.0) | 150 (3.8) | |
| Holoprosencephaly | 26 (0.9) | 11 (2.3) | <5 (†) | <5 (†) | 0 (0.0) | 42 (1.1) | |
| Hypoplastic left heart syndrome | 66 (2.2) | 7 (1.4) | <5 (†) | <5 (†) | 0 (0.0) | 80 (2.0) | |
| Hypospadias | 1255 (82.4) | 183 (74.1) | 59 (40.5) | 31 (54.5) | 0 (0.0) | 1543 (76.6) | 1 |
| Interrupted aortic arch (IAA) | 14 (0.5) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 16 (0.4) | |
| Limb deficiencies (reduction defects) | 110 (3.7) | 16 (3.3) | 13 (4.6) | <5 (†) | 0 (0.0) | 140 (3.6) | |
| Omphalocele | 51 (1.7) | 15 (3.1) | <5 (†) | <5 (†) | 0 (0.0) | 74 (1.9) | |
| Pulmonary valve atresia | 30 (1.0) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 35 (0.9) | |
| Pulmonary valve atresia and stenosis | 281 (9.5) | 53 (10.9) | 42 (14.8) | 13 (11.9) | <5 (†) | 393 (10.0) | |
| Rectal and large intestinal atresia / stenosis | 150 (5.1) | 14 (2.9) | 10 (3.5) | 5 (4.6) | <5 (†) | 183 (4.7) | |
| Renal agenesis / hypoplasia | 198 (6.7) | 24 (5.0) | 21 (7.4) | 7 (6.4) | 0 (0.0) | 254 (6.5) | |
| Single ventricle | 22 (0.7) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 25 (0.6) | |
| Small intestinal atresia / stenosis | 101 (3.4) | 17 (3.5) | 5 (1.8) | <5 (†) | 0 (0.0) | 130 (3.3) | |
| Spina bifida without anencephaly | 81 (2.7) | 15 (3.1) | 13 (4.6) | <5 (†) | 0 (0.0) | 111 (2.8) | |
| Tetralogy of Fallot (TOF) | 110 (3.7) | 19 (3.9) | 7 (2.5) | 7 (6.4) | 0 (0.0) | 144 (3.7) | |
| Total anomalous pulmonary venous connection (TAPVC) | 29 (1.0) | <5 (†) | 5 (1.8) | 0 (0.0) | 0 (0.0) | 38 (1.0) | |
| Transposition of the great arteries (TGA) | 84 (2.8) | 7 (1.4) | 10 (3.5) | <5 (†) | 0 (0.0) | 104 (2.6) | |
| Tricuspid valve atresia and stenosis | 12 (0.4) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 19 (0.5) | |
| Trisomy 13 | 20 (0.7) | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 22 (0.6) | |
| Trisomy 18 | 38 (1.3) | 13 (2.7) | <5 (†) | <5 (†) | 0 (0.0) | 59 (1.5) | |
| Trisomy 21 (Down syndrome) | 399 (13.4) | 51 (10.5) | 57 (20.1) | 22 (20.1) | 0 (0.0) | 538 (13.7) | |
| Turner syndrome | 30 (2.1) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 34 (1.8) | 2 |
| Ventricular septal defect | 1630 (54.9) | 252 (52.0) | 199 (70.1) | 63 (57.7) | <5 (†) | 2182 (55.5) | |
| Total live births | 296921 | 48482 | 28404 | 10921 | 386 | 393256 | 3 |
| Male Live Births | 152299 | 24702 | 14578 | 5684 | 188 | 201545 | |
| Female Live Births | 144622 | 23780 | 13826 | 5237 | 198 | 191711 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
|||||||
| Indiana Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 145 (4.3) | 5 (0.9) | 150 (3.8) |
| Trisomy 13 | 9 (0.3) | 13 (2.4) | 22 (0.6) |
| Trisomy 18 | 29 (0.9) | 30 (5.6) | 59 (1.5) |
| Trisomy 21 (Down syndrome) | 245 (7.2) | 293 (54.7) | 538 (13.7) |
| Total live births | 339648 | 53595 | 393256 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
|||
| Indiana Notes on Specific Birth Defects |
|
| Defect | Site Comment |
|---|---|
| Tricuspid valve atresia | Tricuspid valve atresia and stenosis are not coded separately |
| Universal comment | Probable cases are included |