Louisiana
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 23 (1.7) 15 (1.4) <5 (†) <5 (†) <5 (†) 43 (1.5)
Anophthalmia / microphthalmia 21 (1.5) 20 (1.9) 8 (3.2) 0 (0.0) 0 (0.0) 52 (1.9)
Anotia / microtia 23 (1.7) 18 (1.7) 14 (5.6) 0 (0.0) 0 (0.0) 56 (2.0)
Aortic valve stenosis 20 (1.4) 8 (0.8) 8 (3.2) <5 (†) 0 (0.0) 37 (1.3)
Atrial septal defect 1511 (109.0) 1354 (130.0) 286 (115.0) 41 (87.4) 14 (115.2) 3288 (117.4)
Atrioventricular septal defect (endocardial cushion defect) 110 (7.9) 98 (9.4) 20 (8.0) <5 (†) <5 (†) 241 (8.6)
Biliary atresia 11 (0.8) 9 (0.9) 0 (0.0) 0 (0.0) 0 (0.0) 21 (0.7)
Bladder exstrophy 0 (0.0) <5 (†) <5 (†) 0 (0.0) 0 (0.0) <5 (†)
Choanal atresia 16 (1.2) <5 (†) <5 (†) 0 (0.0) <5 (†) 24 (0.9)
Cleft lip alone (without cleft palate) 46 (3.3) 17 (1.6) 13 (5.2) <5 (†) 0 (0.0) 81 (2.9)
Cleft lip with cleft palate 97 (7.0) 59 (5.7) 21 (8.4) <5 (†) 0 (0.0) 185 (6.6)
Cleft palate alone (without cleft lip) 155 (11.2) 65 (6.2) 23 (9.3) <5 (†) <5 (†) 252 (9.0)
Clubfoot 184 (13.3) 158 (15.2) 29 (11.7) <5 (†) 0 (0.0) 381 (13.6)
Coarctation of aorta 77 (5.6) 46 (4.4) 12 (4.8) <5 (†) 0 (0.0) 136 (4.9)
Common truncus (truncus arteriosus or TA) 11 (1.0) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 14 (0.6)
Congenital cataract 36 (2.6) 22 (2.1) 6 (2.4) <5 (†) 0 (0.0) 65 (2.3)
Congenital posterior urethral valves 13 (1.8) 22 (4.2) <5 (†) 0 (0.0) 0 (0.0) 39 (2.7) 1
Craniosynostosis 154 (11.1) 84 (8.1) 22 (8.8) <5 (†) <5 (†) 272 (9.7)
Deletion 22q11.2 28 (2.0) 20 (1.9) <5 (†) 0 (0.0) 0 (0.0) 50 (1.8)
Dextro-Transposition of great arteries (d-TGA) 37 (2.7) 19 (1.8) 9 (3.6) <5 (†) 0 (0.0) 68 (2.4)
Diaphragmatic hernia 36 (2.6) 27 (2.6) <5 (†) <5 (†) 0 (0.0) 69 (2.5)
Double outlet right ventricle (DORV) 38 (2.7) 34 (3.3) 5 (2.0) <5 (†) 0 (0.0) 80 (2.9)
Ebstein anomaly 12 (0.9) 7 (0.7) <5 (†) <5 (†) 0 (0.0) 26 (0.9)
Encephalocele 10 (0.7) 16 (1.5) <5 (†) 0 (0.0) 0 (0.0) 30 (1.1)
Esophageal atresia / tracheoesophageal fistula 25 (1.8) 25 (2.4) 7 (2.8) 0 (0.0) <5 (†) 59 (2.1)
Gastroschisis 45 (3.2) 36 (3.5) <5 (†) <5 (†) 0 (0.0) 89 (3.2)
Holoprosencephaly 9 (0.6) 17 (1.6) 5 (2.0) 0 (0.0) 0 (0.0) 33 (1.2)
Hypoplastic left heart syndrome 33 (2.4) 21 (2.0) 5 (2.0) <5 (†) 0 (0.0) 61 (2.2)
Hypospadias 594 (83.5) 369 (69.8) 57 (44.7) 16 (65.6) <5 (†) 1075 (75.1) 1
Interrupted aortic arch (IAA) 14 (1.0) 12 (1.2) <5 (†) <5 (†) 0 (0.0) 28 (1.0)
Limb deficiencies (reduction defects) 35 (2.5) 32 (3.1) 6 (2.4) <5 (†) 0 (0.0) 77 (2.7)
Omphalocele 28 (2.0) 19 (1.8) 5 (2.0) 0 (0.0) 0 (0.0) 53 (1.9)
Pulmonary valve atresia 14 (1.0) 15 (1.4) <5 (†) 0 (0.0) 0 (0.0) 31 (1.1)
Pulmonary valve atresia and stenosis 168 (12.1) 174 (16.7) 40 (16.1) <5 (†) <5 (†) 397 (14.2)
Rectal and large intestinal atresia / stenosis 48 (3.5) 47 (4.5) 16 (6.4) <5 (†) <5 (†) 115 (4.1)
Renal agenesis / hypoplasia 92 (6.6) 48 (4.6) 13 (5.2) <5 (†) 0 (0.0) 160 (5.7)
Single ventricle 5 (0.4) <5 (†) 5 (2.0) 0 (0.0) 0 (0.0) 14 (0.5)
Small intestinal atresia / stenosis 60 (4.3) 47 (4.5) 10 (4.0) 0 (0.0) 0 (0.0) 122 (4.4)
Spina bifida without anencephaly 38 (2.7) 27 (2.6) 14 (5.6) 0 (0.0) 0 (0.0) 81 (2.9)
Tetralogy of Fallot (TOF) 71 (5.1) 54 (5.2) 8 (3.2) 0 (0.0) <5 (†) 137 (4.9)
Total anomalous pulmonary venous connection (TAPVC) 13 (1.2) 8 (1.0) 8 (4.0) <5 (†) 0 (0.0) 32 (1.4)
Transposition of the great arteries (TGA) 43 (3.1) 24 (2.3) 14 (5.6) <5 (†) 0 (0.0) 84 (3.0)
Tricuspid valve atresia 9 (0.6) <5 (†) 6 (2.4) 0 (0.0) 0 (0.0) 19 (0.7)
Tricuspid valve atresia and stenosis 12 (0.9) 7 (0.7) 7 (2.8) 0 (0.0) 0 (0.0) 26 (0.9)
Trisomy 13 13 (0.9) 17 (1.6) <5 (†) 0 (0.0) 0 (0.0) 33 (1.2)
Trisomy 18 31 (2.2) 31 (3.0) 9 (3.6) 0 (0.0) 0 (0.0) 73 (2.6)
Trisomy 21 (Down syndrome) 198 (14.3) 113 (10.9) 55 (22.1) 7 (14.9) <5 (†) 388 (13.8)
Turner syndrome 17 (2.5) 9 (1.8) <5 (†) 0 (0.0) 0 (0.0) 28 (2.0) 2
Ventricular septal defect 885 (63.8) 638 (61.3) 222 (89.3) 21 (44.8) 5 (41.2) 1811 (64.6)
Total live births 138624 104125 24863 4692 1215 280181 3
Male Live Births 71170 52837 12742 2439 603 143231
Female Live Births 67454 51286 12121 2253 612 136948
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Louisiana
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 84 (3.5) 5 (1.3) 89 (3.2)
Trisomy 13 25 (1.0) 8 (2.1) 33 (1.2)
Trisomy 18 38 (1.6) 35 (9.1) 73 (2.6)
Trisomy 21 (Down syndrome) 200 (8.3) 188 (49.0) 388 (13.8)
Total live births 241800 38381 280181
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age