Michigan
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 39 (1.1) <6 (†) <6 (†) <6 (†) 0 (0.0) 48 (0.9)
Anophthalmia / microphthalmia 65 (1.8) 22 (2.3) 6 (1.8) 6 (3.1) 0 (0.0) 108 (2.1)
Anotia / microtia 94 (2.7) 25 (2.6) 13 (4.0) 7 (3.7) <6 (†) 160 (3.0)
Aortic valve stenosis 117 (3.3) 10 (1.0) <6 (†) 7 (3.7) <6 (†) 153 (2.9)
Atrial septal defect 7616 (215.5) 3162 (324.9) 734 (223.8) 409 (213.9) 91 (283.9) 12929 (246.3)
Atrioventricular septal defect (endocardial cushion defect) 158 (4.5) 54 (5.5) 15 (4.6) <6 (†) 0 (0.0) 249 (4.7)
Biliary atresia 67 (1.9) 36 (3.7) 6 (1.8) <6 (†) 0 (0.0) 122 (2.3)
Bladder exstrophy 7 (0.2) <6 (†) <6 (†) 0 (0.0) 0 (0.0) 18 (0.3)
Choanal atresia 82 (2.3) 18 (1.8) 8 (2.4) <6 (†) <6 (†) 127 (2.4)
Cleft lip alone (without cleft palate) 295 (8.3) 60 (6.2) 20 (6.1) 14 (7.3) <6 (†) 421 (8.0)
Cleft lip with cleft palate 334 (9.5) 69 (7.1) 39 (11.9) 15 (7.8) <6 (†) 508 (9.7)
Cleft palate alone (without cleft lip) 467 (13.2) 99 (10.2) 37 (11.3) 24 (12.6) 7 (21.8) 700 (13.3)
Cloacal exstrophy <6 (†) <6 (†) <6 (†) 0 (0.0) 0 (0.0) 11 (0.2)
Clubfoot 848 (24.0) 225 (23.1) 64 (19.5) 38 (19.9) 12 (37.4) 1309 (24.9)
Coarctation of aorta 355 (10.0) 70 (7.2) 30 (9.1) 17 (8.9) <6 (†) 530 (10.1)
Common truncus (truncus arteriosus or TA) 44 (1.2) 15 (1.5) 8 (2.4) <6 (†) 0 (0.0) 77 (1.5)
Congenital cataract 101 (2.9) 29 (3.0) 7 (2.1) <6 (†) 0 (0.0) 156 (3.0)
Congenital posterior urethral valves 60 (3.3) 28 (5.7) <6 (†) <6 (†) 0 (0.0) 111 (4.1) 1
Craniosynostosis 1086 (30.7) 227 (23.3) 80 (24.4) 54 (28.2) <6 (†) 1599 (30.5)
Deletion 22q11.2 69 (2.0) 15 (1.5) 7 (2.1) <6 (†) 0 (0.0) 99 (1.9)
Dextro-Transposition of great arteries (d-TGA) 145 (4.1) 32 (3.3) 12 (3.7) <6 (†) <6 (†) 217 (4.1)
Diaphragmatic hernia 159 (4.5) 41 (4.2) 16 (4.9) <6 (†) <6 (†) 250 (4.8)
Double outlet right ventricle (DORV) 108 (3.1) 37 (3.8) 13 (4.0) <6 (†) <6 (†) 181 (3.4)
Ebstein anomaly 29 (0.8) 7 (0.7) <6 (†) <6 (†) <6 (†) 43 (0.8)
Encephalocele 43 (1.2) 14 (1.4) <6 (†) 0 (0.0) 0 (0.0) 64 (1.2)
Esophageal atresia / tracheoesophageal fistula 124 (3.5) 15 (1.5) 6 (1.8) <6 (†) 0 (0.0) 158 (3.0)
Gastroschisis 129 (3.7) 29 (3.0) 14 (4.3) <6 (†) <6 (†) 186 (3.5)
Holoprosencephaly 18 (0.5) 17 (1.7) <6 (†) <6 (†) <6 (†) 51 (1.0)
Hypoplastic left heart syndrome 161 (4.6) 42 (4.3) 16 (4.9) <6 (†) 6 (18.7) 259 (4.9)
Hypospadias 1845 (102.2) 448 (90.9) 102 (60.6) 77 (78.8) 11 (66.7) 2697 (100.6) 1
Interrupted aortic arch (IAA) 33 (0.9) 13 (1.3) <6 (†) 6 (3.1) 0 (0.0) 57 (1.1)
Limb deficiencies (reduction defects) 183 (5.2) 63 (6.5) 18 (5.5) 7 (3.7) <6 (†) 294 (5.6)
Omphalocele 101 (2.9) 106 (10.9) 7 (2.1) <6 (†) 0 (0.0) 230 (4.4)
Pulmonary valve atresia 76 (2.2) 24 (2.5) <6 (†) <6 (†) <6 (†) 113 (2.2)
Pulmonary valve atresia and stenosis 467 (13.2) 148 (15.2) 39 (11.9) 10 (5.2) <6 (†) 725 (13.8)
Rectal and large intestinal atresia / stenosis 160 (4.5) 36 (3.7) 14 (4.3) 6 (3.1) 0 (0.0) 231 (4.4)
Renal agenesis / hypoplasia 329 (9.3) 80 (8.2) 25 (7.6) 8 (4.2) <6 (†) 501 (9.5)
Single ventricle 95 (2.7) 30 (3.1) 12 (3.7) <6 (†) <6 (†) 161 (3.1)
Small intestinal atresia / stenosis 137 (3.9) 52 (5.3) 16 (4.9) 8 (4.2) 0 (0.0) 230 (4.4)
Spina bifida without anencephaly 145 (4.1) 26 (2.7) 20 (6.1) <6 (†) <6 (†) 223 (4.2)
Tetralogy of Fallot (TOF) 203 (5.7) 63 (6.5) 13 (4.0) 9 (4.7) <6 (†) 326 (6.2)
Total anomalous pulmonary venous connection (TAPVC) 34 (1.0) 9 (0.9) <6 (†) <6 (†) 0 (0.0) 59 (1.1)
Transposition of the great arteries (TGA) 147 (4.2) 33 (3.4) 12 (3.7) <6 (†) <6 (†) 222 (4.2)
Tricuspid valve atresia 35 (1.0) 11 (1.1) <6 (†) <6 (†) 0 (0.0) 51 (1.0)
Tricuspid valve atresia and stenosis 35 (1.0) 11 (1.1) <6 (†) <6 (†) 0 (0.0) 51 (1.0)
Trisomy 13 32 (0.9) 8 (0.8) <6 (†) <6 (†) 0 (0.0) 48 (0.9)
Trisomy 18 68 (1.9) 21 (2.2) 8 (2.4) 7 (3.7) <6 (†) 115 (2.2)
Trisomy 21 (Down syndrome) 489 (13.8) 124 (12.7) 59 (18.0) 19 (9.9) <6 (†) 794 (15.1)
Turner syndrome 76 (4.4) 20 (4.2) <6 (†) <6 (†) <6 (†) 111 (4.3) 2
Ventricular septal defect 2609 (73.8) 774 (79.5) 246 (75.0) 134 (70.1) 20 (62.4) 4128 (78.6)
Total live births 353336 97337 32799 19118 3205 524873 3
Male Live Births 180607 49293 16821 9774 1648 267964
Female Live Births 172724 48037 15978 9343 1557 256896
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sexcases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- <6 (†) denotes censored count and prevalence when 1-5 cases observed
*- Data for totals include unknown/other race
Michigan
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 176 (4.0) 10 (1.2) 186 (3.5)
Trisomy 13 32 (0.7) 16 (1.9) 48 (0.9)
Trisomy 18 67 (1.5) 48 (5.6) 115 (2.2)
Trisomy 21 (Down syndrome) 461 (10.5) 333 (39.1) 794 (15.1)
Total live births 439711 85162 524873
Notes
†- <6 (†) denotes censored count and prevalence when 1-5 cases observed
*- Data for totals include unknown/other maternal age