| Minnesota Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
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| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
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| Anencephaly | 15 (0.7) | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 21 (0.7) | |
| Anophthalmia / microphthalmia | 26 (1.3) | 10 (2.6) | 5 (1.9) | 8 (3.2) | <5 (†) | 50 (1.6) | |
| Anotia / microtia | 62 (3) | 7 (1.8) | 27 (10.3) | 18 (7.2) | <5 (†) | 121 (3.9) | |
| Aortic valve stenosis | 46 (2.2) | 5 (1.3) | <5 (†) | 5 (2) | <5 (†) | 61 (2) | |
| Atrial septal defect | 613 (29.5) | 158 (40.7) | 93 (35.5) | 73 (29.1) | 49 (119.8) | 1020 (32.6) | 1 |
| Atrioventricular septal defect (Endocardial cushion defect) | 96 (4.6) | 37 (9.5) | 6 (2.3) | 7 (2.8) | <5 (†) | 153 (4.9) | |
| Biliary atresia | 11 (0.5) | 5 (1.3) | <5 (†) | <5 (†) | 0 (0.0) | 19 (0.6) | |
| Bladder exstrophy | 6 (0.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 7 (0.2) | |
| Choanal atresia | 31 (1.5) | <5 (†) | <5 (†) | <5 (†) | <5 (†) | 35 (1.1) | |
| Cleft lip alone | 58 (2.8) | 16 (4.1) | 14 (5.3) | 10 (4) | <5 (†) | 105 (3.4) | |
| Cleft lip with cleft palate | 120 (5.8) | 17 (4.4) | 20 (7.6) | 17 (6.8) | 5 (12.2) | 183 (5.9) | |
| Cleft palate alone | 156 (7.5) | 23 (5.9) | 19 (7.2) | 28 (11.2) | 12 (29.3) | 250 (8) | |
| Cloacal extrophy | <5 (†) | 0 (0.0) | <5 (†) | 0 (0.0) | 0 (0.0) | 6 (0.2) | |
| Clubfoot | 330 (15.9) | 61 (15.7) | 29 (11.1) | 22 (8.8) | 9 (22) | 466 (14.9) | |
| Coarctation of the aorta | 120 (5.8) | 21 (5.4) | 11 (4.2) | 8 (3.2) | <5 (†) | 165 (5.3) | |
| Common truncus (truncus arteriosus) | 8 (0.4) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 12 (0.4) | |
| Congenital cataract | 51 (2.5) | 19 (4.9) | 7 (2.7) | 12 (4.8) | <5 (†) | 97 (3.1) | |
| Congenital posterior urethral valves | 25 (2.3) | 11 (5.6) | <5 (†) | <5 (†) | <5 (†) | 44 (2.8) | 2 |
| Craniosynostosis | 201 (9.7) | 17 (4.4) | 18 (6.9) | 6 (2.4) | <5 (†) | 252 (8.1) | |
| Deletion 22q11.2 | 29 (1.4) | 7 (1.8) | <5 (†) | <5 (†) | 0 (0.0) | 39 (1.2) | |
| Dextro-Transposition of great arteries (d-TGA) | 68 (3.3) | 12 (3.1) | <5 (†) | 5 (2) | <5 (†) | 92 (2.9) | |
| Diaphragmatic hernia | 68 (3.3) | 16 (4.1) | 6 (2.3) | 5 (2) | 0 (0.0) | 95 (3) | |
| Double outlet right ventricle | 36 (1.7) | 18 (4.6) | 5 (1.9) | 9 (3.6) | <5 (†) | 73 (2.3) | |
| Ebstein anomaly | 20 (1) | <5 (†) | <5 (†) | <5 (†) | <5 (†) | 30 (1) | |
| Encephalocele | 19 (0.9) | <5 (†) | <5 (†) | <5 (†) | <5 (†) | 28 (0.9) | |
| Esophageal atresia / tracheoesophageal fistula | 54 (2.6) | 8 (2.1) | <5 (†) | <5 (†) | <5 (†) | 72 (2.3) | |
| Gastroschisis | 51 (2.5) | 9 (2.3) | 10 (3.8) | 6 (2.4) | <5 (†) | 80 (2.6) | |
| Holoprosencephaly | 10 (0.5) | 9 (2.3) | 5 (1.9) | <5 (†) | <5 (†) | 28 (0.9) | |
| Hypoplastic left heart syndrome | 43 (2.1) | 12 (3.1) | 7 (2.7) | <5 (†) | <5 (†) | 68 (2.2) | |
| Hypospadias | 685 (64.3) | 174 (88.3) | 41 (30.8) | 26 (20.2) | 8 (38.6) | 965 (60.4) | 2 |
| Interrupted aortic arch | 18 (0.9) | 5 (1.3) | <5 (†) | <5 (†) | 0 (0.0) | 26 (0.8) | |
| Limb deficiencies (reduction defects) | 80 (3.8) | 24 (6.2) | 15 (5.7) | 7 (2.8) | <5 (†) | 131 (4.2) | |
| Omphalocele | 47 (2.3) | 16 (4.1) | <5 (†) | <5 (†) | 0 (0.0) | 71 (2.3) | |
| Pulmonary valve atresia | 23 (1.1) | 8 (2.1) | 7 (2.7) | 6 (2.4) | <5 (†) | 47 (1.5) | |
| Pulmonary valve atresia and stenosis | 292 (14) | 76 (19.6) | 45 (17.2) | 26 (10.4) | <5 (†) | 458 (14.6) | |
| Rectal and large intestinal atresia / stenosis | 90 (4.3) | 15 (3.9) | 17 (6.5) | 6 (2.4) | <5 (†) | 139 (4.4) | |
| Renal agenesis / hypoplasia | 150 (7.2) | 30 (7.7) | 18 (6.9) | 14 (5.6) | <5 (†) | 220 (7) | |
| Single ventricle | 8 (0.4) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 10 (0.3) | |
| Small intestinal atresia / stenosis | 66 (3.2) | 16 (4.1) | 13 (5) | 6 (2.4) | <5 (†) | 112 (3.6) | |
| Spina bifida without anencephalus | 63 (3) | 11 (2.8) | 5 (1.9) | <5 (†) | <5 (†) | 86 (2.8) | |
| Tetralogy of Fallot | 101 (4.9) | 11 (2.8) | 7 (2.7) | 9 (3.6) | <5 (†) | 132 (4.2) | |
| Total anomalous pulmonary venous connection | 15 (0.7) | 5 (1.3) | 5 (1.9) | 7 (2.8) | <5 (†) | 35 (1.1) | |
| Transposition of the great arteries (TGA) | 79 (3.8) | 15 (3.9) | 6 (2.3) | 5 (2) | <5 (†) | 111 (3.5) | |
| Tricuspid valve atresia | 14 (0.7) | 6 (1.5) | <5 (†) | <5 (†) | <5 (†) | 25 (0.8) | |
| Tricuspid valve atresia and stenosis | 22 (1.1) | 12 (3.1) | <5 (†) | <5 (†) | <5 (†) | 46 (1.5) | |
| Trisomy 13 | 7 (0.3) | 10 (2.6) | <5 (†) | <5 (†) | 0 (0.0) | 25 (0.8) | |
| Trisomy 18 | 30 (1.4) | 32 (8.2) | <5 (†) | 6 (2.4) | 0 (0.0) | 72 (2.3) | |
| Trisomy 21 (Down syndrome) | 309 (14.9) | 102 (26.3) | 47 (17.9) | 31 (12.3) | 10 (24.4) | 512 (16.4) | |
| Turner syndrome | 34 (3.4) | 5 (2.6) | <5 (†) | 6 (4.9) | <5 (†) | 51 (3.3) | 3 |
| Ventricular septal defect | 1577 (75.8) | 321 (82.8) | 205 (78.2) | 131 (52.2) | 52 (127.1) | 2344 (75) | 4 |
| Total live births | 207947 | 38788 | 26210 | 25107 | 4091 | 312726 | 5 |
| Male live births | 106543 | 19709 | 13313 | 12863 | 2071 | 159865 | |
| Female live births | 101402 | 19077 | 12897 | 12244 | 2020 | 152857 | |
| Notes 1- Data for this condition exclude inlet ventricular septal defect. 2- Data for this condition include male and unknown infant sex cases only. Prevalenece is calculated per 10,000 male live births. 3- Data for this condition include female and unknown infant sex cases only. Prevalenece is calculated per 10,000 female live births. 4- Data for this condition include inlet ventricular septal defect. 5- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
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| Minnesota Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 76 (3.1) | <5 (†) | 80 (2.6) |
| Trisomy 13 | 11 (0.4) | 14 (2.2) | 25 (0.8) |
| Trisomy 18 | 30 (1.2) | 42 (6.5) | 72 (2.3) |
| Trisomy 21 (Down syndrome) | 236 (9.5) | 276 (42.5) | 512 (16.4) |
| Total live births | 247807 | 64904 | 312726 |
| Notes Data for conditions exclude probable and possible cases †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
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