| Missouri Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
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| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
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| Anencephaly | 59 (2.3) | 9 (1.7) | <5 (†) | 0 (0.0) | 0 (0.0) | 73 (2.1) | |
| Anophthalmia / microphthalmia | 27 (1.0) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 32 (0.9) | |
| Anotia / microtia | 28 (1.1) | 6 (1.1) | <5 (†) | 0 (0.0) | 0 (0.0) | 37 (1.0) | |
| Aortic valve stenosis | 47 (1.8) | 8 (1.5) | 5 (2.2) | <5 (†) | 0 (0.0) | 63 (1.8) | |
| Atrial septal defect | 4710 (181.0) | 1413 (265.1) | 427 (185.1) | 187 (182.4) | 38 (294.8) | 6887 (195.2) | |
| Atrioventricular septal defect (endocardial cushion defect) | 150 (5.8) | 44 (8.3) | 11 (4.8) | <5 (†) | 0 (0.0) | 211 (6.0) | |
| Biliary atresia | 77 (3.0) | 56 (10.5) | 13 (5.6) | 5 (4.9) | <5 (†) | 161 (4.6) | |
| Bladder exstrophy | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | <5 (†) | 6 (0.2) | |
| Choanal atresia | 46 (1.8) | 8 (1.5) | 6 (2.6) | 0 (0.0) | <5 (†) | 62 (1.8) | |
| Cleft lip alone (without cleft palate) | 115 (4.4) | 15 (2.8) | 7 (3.0) | <5 (†) | 0 (0.0) | 140 (4.0) | |
| Cleft lip with cleft palate | 193 (7.4) | 28 (5.3) | 13 (5.6) | <5 (†) | <5 (†) | 243 (6.9) | |
| Cleft palate alone (without cleft lip) | 204 (7.8) | 42 (7.9) | 17 (7.4) | 6 (5.9) | <5 (†) | 280 (7.9) | |
| Cloacal exstrophy | 0 (0.0) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | <5 (†) | |
| Clubfoot | 745 (28.6) | 123 (23.1) | 45 (19.5) | 22 (21.5) | 5 (38.8) | 956 (27.1) | |
| Coarctation of aorta | 193 (7.4) | 38 (7.1) | 18 (7.8) | <5 (†) | 0 (0.0) | 256 (7.3) | |
| Common truncus (truncus arteriosus or TA) | 16 (0.6) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 20 (0.6) | |
| Congenital cataract | 60 (2.3) | 16 (3.0) | 5 (2.2) | <5 (†) | <5 (†) | 87 (2.5) | |
| Congenital posterior urethral valves | 37 (2.8) | 13 (4.8) | <5 (†) | <5 (†) | 0 (0.0) | 56 (3.1) | 1 |
| Craniosynostosis | 325 (12.5) | 35 (6.6) | 18 (7.8) | 11 (10.7) | <5 (†) | 399 (11.3) | |
| Deletion 22q11.2 | 37 (1.4) | 13 (2.4) | <5 (†) | 0 (0.0) | 0 (0.0) | 54 (1.5) | |
| Dextro-Transposition of great arteries (d-TGA) | 95 (3.7) | 13 (2.4) | 7 (3.0) | 5 (4.9) | 0 (0.0) | 122 (3.5) | |
| Diaphragmatic hernia | 129 (5.0) | 36 (6.8) | 7 (3.0) | <5 (†) | <5 (†) | 175 (5.0) | |
| Double outlet right ventricle (DORV) | 79 (3.0) | 21 (3.9) | <5 (†) | <5 (†) | 0 (0.0) | 107 (3.0) | |
| Ebstein anomaly | 25 (1.0) | 6 (1.1) | <5 (†) | 0 (0.0) | <5 (†) | 34 (1.0) | |
| Encephalocele | 44 (1.7) | 7 (1.3) | <5 (†) | 0 (0.0) | 0 (0.0) | 53 (1.5) | |
| Esophageal atresia / tracheoesophageal fistula | 78 (3.0) | 12 (2.3) | <5 (†) | <5 (†) | 0 (0.0) | 93 (2.6) | |
| Gastroschisis | 101 (3.9) | 16 (3.0) | 12 (5.2) | <5 (†) | <5 (†) | 135 (3.8) | |
| Holoprosencephaly | 28 (1.1) | 10 (1.9) | <5 (†) | <5 (†) | 0 (0.0) | 41 (1.2) | |
| Hypoplastic left heart syndrome | 111 (4.3) | 30 (5.6) | 5 (2.2) | <5 (†) | <5 (†) | 150 (4.3) | |
| Hypospadias | 1648 (123.4) | 272 (100.4) | 87 (74.8) | 46 (87.0) | <5 (†) | 2080 (115.1) | 1 |
| Interrupted aortic arch (IAA) | 22 (0.8) | 5 (0.9) | <5 (†) | <5 (†) | 0 (0.0) | 33 (0.9) | |
| Limb deficiencies (reduction defects) | 137 (5.3) | 32 (6.0) | 12 (5.2) | 7 (6.8) | <5 (†) | 194 (5.5) | |
| Omphalocele | 78 (3.0) | 17 (3.2) | 5 (2.2) | 6 (5.9) | <5 (†) | 112 (3.2) | |
| Pulmonary valve atresia | 43 (1.7) | 12 (2.3) | <5 (†) | <5 (†) | 0 (0.0) | 59 (1.7) | |
| Pulmonary valve atresia and stenosis | 196 (7.5) | 53 (9.9) | 19 (8.2) | 9 (8.8) | 0 (0.0) | 279 (7.9) | |
| Rectal and large intestinal atresia / stenosis | 114 (4.4) | 21 (3.9) | 14 (6.1) | 8 (7.8) | <5 (†) | 163 (4.6) | |
| Renal agenesis / hypoplasia | 229 (8.8) | 50 (9.4) | 16 (6.9) | 6 (5.9) | <5 (†) | 304 (8.6) | |
| Single ventricle | 61 (2.3) | 10 (1.9) | 5 (2.2) | <5 (†) | 0 (0.0) | 77 (2.2) | |
| Small intestinal atresia / stenosis | 83 (3.2) | 28 (5.3) | 14 (6.1) | 5 (4.9) | 0 (0.0) | 132 (3.7) | |
| Spina bifida without anencephaly | 122 (4.7) | 18 (3.4) | 12 (5.2) | 7 (6.8) | <5 (†) | 162 (4.6) | |
| Tetralogy of Fallot (TOF) | 129 (5.0) | 38 (7.1) | <5 (†) | 7 (6.8) | 0 (0.0) | 180 (5.1) | |
| Total anomalous pulmonary venous connection (TAPVC) | 29 (1.1) | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 37 (1.0) | |
| Transposition of the great arteries (TGA) | 103 (4.0) | 16 (3.0) | 7 (3.0) | 5 (4.9) | 0 (0.0) | 133 (3.8) | |
| Tricuspid valve atresia | 27 (1.0) | 5 (0.9) | <5 (†) | <5 (†) | 0 (0.0) | 36 (1.0) | |
| Tricuspid valve atresia and stenosis | 27 (1.0) | 5 (0.9) | <5 (†) | <5 (†) | 0 (0.0) | 36 (1.0) | |
| Trisomy 13 | 23 (0.9) | 7 (1.3) | 0 (0.0) | <5 (†) | 0 (0.0) | 32 (0.9) | |
| Trisomy 18 | 67 (2.6) | 12 (2.3) | 8 (3.5) | <5 (†) | 0 (0.0) | 93 (2.6) | |
| Trisomy 21 (Down syndrome) | 419 (16.1) | 79 (14.8) | 49 (21.2) | 17 (16.6) | <5 (†) | 577 (16.4) | |
| Turner syndrome | 66 (5.2) | 11 (4.2) | <5 (†) | <5 (†) | <5 (†) | 84 (4.9) | 2 |
| Ventricular septal defect | 1506 (57.9) | 333 (62.5) | 151 (65.5) | 46 (44.9) | <5 (†) | 2072 (58.7) | |
| Total live births | 260272 | 53310 | 23065 | 10253 | 1289 | 352884 | 3 |
| Male Live Births | 133589 | 27096 | 11634 | 5286 | 643 | 180689 | |
| Female Live Births | 126678 | 26210 | 11429 | 4967 | 646 | 172183 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
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| Missouri Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 129 (4.3) | 6 (1.2) | 135 (3.8) |
| Trisomy 13 | 18 (0.6) | 14 (2.7) | 32 (0.9) |
| Trisomy 18 | 46 (1.5) | 47 (9.1) | 93 (2.6) |
| Trisomy 21 (Down syndrome) | 311 (10.3) | 266 (51.8) | 577 (16.4) |
| Total live births | 301442 | 51370 | 352884 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
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