Mississippi
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 7 (0.8) 8 (1.1) <5 (†) 0 (0.0) 0 (0.0) 17 (0.9)
Anophthalmia / microphthalmia 11 (1.2) 13 (1.7) 0 (0.0) <5 (†) 0 (0.0) 26 (1.5)
Anotia / microtia 13 (1.4) 23 (3.1) 5 (5.7) 0 (0.0) 0 (0.0) 42 (2.3)
Aortic valve stenosis 25 (2.8) 8 (1.1) <5 (†) 0 (0.0) <5 (†) 37 (2.1)
Atrial septal defect 2374 (263.4) 2904 (385.9) 244 (279.4) 38 (171.9) 63 (547.8) 5668 (316.7)
Atrioventricular septal defect (endocardial cushion defect) 52 (5.8) 51 (6.8) <5 (†) <5 (†) 0 (0.0) 109 (6.1)
Biliary atresia 15 (1.7) 18 (2.4) <5 (†) <5 (†) 0 (0.0) 35 (2.0)
Bladder exstrophy <5 (†) <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 5 (0.3)
Choanal atresia 14 (1.6) 10 (1.3) <5 (†) 0 (0.0) 0 (0.0) 25 (1.4)
Cleft lip alone (without cleft palate) 54 (6.0) 31 (4.1) 0 (0.0) <5 (†) <5 (†) 91 (5.1)
Cleft lip with cleft palate 56 (6.2) 45 (6.0) <5 (†) <5 (†) 7 (60.9) 119 (6.6)
Cleft palate alone (without cleft lip) 108 (12.0) 54 (7.2) 11 (12.6) 6 (27.1) 10 (87.0) 190 (10.6)
Cloacal exstrophy <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†)
Clubfoot 216 (24.0) 175 (23.3) 15 (17.2) <5 (†) 5 (43.5) 421 (23.5)
Coarctation of aorta 85 (9.4) 67 (8.9) 6 (6.9) 0 (0.0) <5 (†) 163 (9.1)
Common truncus (truncus arteriosus or TA) 5 (0.6) 12 (1.6) 0 (0.0) 0 (0.0) 0 (0.0) 17 (0.9)
Congenital cataract 17 (1.9) 9 (1.2) 0 (0.0) 0 (0.0) <5 (†) 27 (1.5)
Congenital posterior urethral valves 16 (3.5) 19 (5.0) 0 (0.0) 0 (0.0) 0 (0.0) 35 (3.8) 1
Craniosynostosis 209 (23.2) 108 (14.4) 17 (19.5) 7 (31.7) 0 (0.0) 346 (19.3)
Deletion 22q11.2 18 (2.0) 16 (2.1) <5 (†) 0 (0.0) 0 (0.0) 35 (2.0)
Dextro-Transposition of great arteries (d-TGA) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0)
Diaphragmatic hernia 24 (2.7) 21 (2.8) <5 (†) 0 (0.0) 0 (0.0) 50 (2.8)
Double outlet right ventricle (DORV) 39 (4.3) 27 (3.6) <5 (†) <5 (†) 0 (0.0) 75 (4.2)
Ebstein anomaly 8 (0.9) 9 (1.2) <5 (†) 0 (0.0) <5 (†) 22 (1.2)
Encephalocele 5 (0.6) 18 (2.4) 0 (0.0) <5 (†) 0 (0.0) 25 (1.4)
Esophageal atresia / tracheoesophageal fistula 23 (2.6) 21 (2.8) <5 (†) 0 (0.0) <5 (†) 47 (2.6)
Gastroschisis 33 (3.7) 30 (4.0) <5 (†) 0 (0.0) 0 (0.0) 67 (3.7)
Holoprosencephaly 10 (1.1) 13 (1.7) 0 (0.0) 0 (0.0) <5 (†) 25 (1.4)
Hypoplastic left heart syndrome 39 (4.3) 43 (5.7) <5 (†) <5 (†) <5 (†) 86 (4.8)
Hypospadias 393 (85.3) 294 (77.0) 18 (40.5) 5 (43.1) <5 (†) 723 (79.2) 1
Interrupted aortic arch (IAA) 7 (0.8) 6 (0.8) 0 (0.0) 0 (0.0) 0 (0.0) 13 (0.7)
Limb deficiencies (reduction defects) 46 (5.1) 47 (6.2) 5 (5.7) 0 (0.0) 0 (0.0) 101 (5.6)
Omphalocele 21 (2.3) 25 (3.3) <5 (†) 0 (0.0) 0 (0.0) 49 (2.7)
Pulmonary valve atresia 12 (1.3) 21 (2.8) <5 (†) 0 (0.0) 0 (0.0) 36 (2.0)
Pulmonary valve atresia and stenosis 81 (9.0) 97 (12.9) 11 (12.6) <5 (†) 0 (0.0) 194 (10.8)
Rectal and large intestinal atresia / stenosis 43 (4.8) 33 (4.4) <5 (†) 0 (0.0) <5 (†) 81 (4.5)
Renal agenesis / hypoplasia 63 (7.0) 72 (9.6) 8 (9.2) <5 (†) <5 (†) 150 (8.4)
Single ventricle 20 (2.2) 30 (4.0) <5 (†) <5 (†) 0 (0.0) 53 (3.0)
Small intestinal atresia / stenosis 20 (2.2) 32 (4.3) 5 (5.7) 0 (0.0) <5 (†) 59 (3.3)
Spina bifida without anencephaly 52 (5.8) 22 (2.9) <5 (†) 0 (0.0) <5 (†) 78 (4.4)
Tetralogy of Fallot (TOF) 53 (5.9) 49 (6.5) 9 (10.3) <5 (†) <5 (†) 114 (6.4)
Total anomalous pulmonary venous connection (TAPVC) 6 (0.7) 13 (1.7) 0 (0.0) 0 (0.0) 0 (0.0) 20 (1.1)
Transposition of the great arteries (TGA) 36 (4.0) 21 (2.8) 5 (5.7) 0 (0.0) 0 (0.0) 64 (3.6)
Tricuspid valve atresia 9 (1.0) 15 (2.0) 0 (0.0) 0 (0.0) 0 (0.0) 24 (1.3)
Tricuspid valve atresia and stenosis 9 (1.0) 15 (2.0) 0 (0.0) 0 (0.0) 0 (0.0) 24 (1.3)
Trisomy 13 9 (1.0) 8 (1.1) 0 (0.0) 0 (0.0) 0 (0.0) 18 (1.0)
Trisomy 18 13 (1.4) 11 (1.5) <5 (†) 0 (0.0) 0 (0.0) 25 (1.4)
Trisomy 21 (Down syndrome) 161 (17.9) 123 (16.3) 35 (40.1) <5 (†) <5 (†) 336 (18.8)
Turner syndrome 22 (5.0) 13 (3.5) 0 (0.0) 0 (0.0) 0 (0.0) 36 (4.1) 2
Ventricular septal defect 614 (68.1) 612 (81.3) 87 (99.6) 13 (58.8) 19 (165.2) 1365 (76.3)
Total live births 90115 75259 8733 2211 1150 178967 3
Male Live Births 46081 38195 4446 1161 583 91253
Female Live Births 44034 37064 4287 1050 567 87714
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Mississippi
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 56 (3.5) <5 (†) 67 (3.7)
Trisomy 13 12 (0.8) <5 (†) 18 (1.0)
Trisomy 18 15 (0.9) 8 (4.1) 25 (1.4)
Trisomy 21 (Down syndrome) 165 (10.3) 99 (51.3) 336 (18.8)
Total live births 159655 19309 178967
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age