Nebraska
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 16 (1.9) 0 (0.0) 5 (2.3) 0 (0.0) <5 (†) 22 (1.8)
Anophthalmia / microphthalmia <5 (†) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 13 (1.1)
Anotia / microtia 23 (2.8) 0 (0.0) 15 (6.8) 0 (0.0) <5 (†) 39 (3.2)
Aortic valve stenosis 17 (2.0) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 22 (1.8)
Atrial septal defect 663 (79.6) 72 (90.6) 155 (70.0) 41 (93.7) 12 (86.1) 984 (79.7)
Atrioventricular septal defect (endocardial cushion defect) 48 (5.8) 7 (8.8) 8 (3.6) <5 (†) 0 (0.0) 68 (5.5)
Biliary atresia 7 (0.8) <5 (†) 0 (0.0) <5 (†) 0 (0.0) 16 (1.3)
Bladder exstrophy <5 (†) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 5 (0.4)
Choanal atresia 15 (1.8) <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 18 (1.5)
Cleft lip alone (without cleft palate) 73 (8.8) 5 (6.3) 17 (7.7) <5 (†) <5 (†) 105 (8.5)
Cleft lip with cleft palate 70 (8.4) 5 (6.3) 18 (8.1) <5 (†) <5 (†) 107 (8.7)
Cleft palate alone (without cleft lip) 82 (9.9) 6 (7.6) 18 (8.1) <5 (†) <5 (†) 117 (9.5)
Cloacal exstrophy <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†)
Clubfoot 246 (29.6) 22 (27.7) 63 (28.5) 9 (20.6) 5 (35.9) 356 (28.8)
Coarctation of aorta 81 (9.7) 7 (8.8) 11 (5.0) <5 (†) <5 (†) 104 (8.4)
Common truncus (truncus arteriosus or TA) 6 (0.7) 0 (0.0) <5 (†) 0 (0.0) <5 (†) 8 (0.6)
Congenital cataract 20 (2.4) <5 (†) 5 (2.3) <5 (†) <5 (†) 32 (2.6)
Congenital posterior urethral valves 14 (3.3) <5 (†) <5 (†) <5 (†) 0 (0.0) 23 (3.6) 1
Craniosynostosis 214 (25.7) 12 (15.1) 36 (16.3) 11 (25.1) <5 (†) 278 (22.5)
Deletion 22q11.2 <5 (†) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) <5 (†)
Dextro-Transposition of great arteries (d-TGA) 31 (3.7) <5 (†) 8 (3.6) <5 (†) 0 (0.0) 47 (3.8)
Diaphragmatic hernia 36 (4.3) <5 (†) 10 (4.5) <5 (†) <5 (†) 56 (4.5)
Double outlet right ventricle (DORV) 16 (1.9) <5 (†) <5 (†) <5 (†) 0 (0.0) 23 (1.9)
Ebstein anomaly 5 (0.6) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 7 (0.6)
Encephalocele 15 (1.8) <5 (†) 5 (2.3) <5 (†) 0 (0.0) 25 (2.0)
Esophageal atresia / tracheoesophageal fistula 25 (3.0) <5 (†) <5 (†) <5 (†) 0 (0.0) 31 (2.5)
Gastroschisis 36 (4.3) <5 (†) 8 (3.6) <5 (†) <5 (†) 51 (4.1)
Holoprosencephaly 16 (1.9) <5 (†) 5 (2.3) 0 (0.0) <5 (†) 25 (2.0)
Hypoplastic left heart syndrome 26 (3.1) <5 (†) 5 (2.3) 0 (0.0) 0 (0.0) 35 (2.8)
Hypospadias 405 (95.4) 39 (95.9) 35 (30.8) 8 (35.2) <5 (†) 511 (81.0) 1
Interrupted aortic arch (IAA) 5 (0.6) <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 7 (0.6)
Limb deficiencies (reduction defects) 53 (6.4) 5 (6.3) 12 (5.4) <5 (†) 0 (0.0) 76 (6.2)
Omphalocele 25 (3.0) 12 (15.1) 8 (3.6) 0 (0.0) 0 (0.0) 46 (3.7)
Pulmonary valve atresia 13 (1.6) 0 (0.0) 6 (2.7) 0 (0.0) 0 (0.0) 21 (1.7)
Pulmonary valve atresia and stenosis 54 (6.5) 5 (6.3) 16 (7.2) <5 (†) 0 (0.0) 80 (6.5)
Rectal and large intestinal atresia / stenosis 40 (4.8) <5 (†) 8 (3.6) <5 (†) 0 (0.0) 56 (4.5)
Renal agenesis / hypoplasia 85 (10.2) 7 (8.8) 14 (6.3) <5 (†) <5 (†) 114 (9.2)
Single ventricle 15 (1.8) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 22 (1.8)
Small intestinal atresia / stenosis 22 (2.6) <5 (†) 14 (6.3) 0 (0.0) <5 (†) 41 (3.3)
Spina bifida without anencephaly 45 (5.4) <5 (†) 10 (4.5) 0 (0.0) <5 (†) 58 (4.7)
Tetralogy of Fallot (TOF) 46 (5.5) <5 (†) 11 (5.0) 0 (0.0) <5 (†) 63 (5.1)
Total anomalous pulmonary venous connection (TAPVC) 8 (1.0) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 11 (0.9)
Transposition of the great arteries (TGA) 31 (3.7) <5 (†) 10 (4.5) <5 (†) 0 (0.0) 49 (4.0)
Tricuspid valve atresia <5 (†) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 6 (0.5)
Tricuspid valve atresia and stenosis <5 (†) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 6 (0.5)
Trisomy 13 15 (1.8) <5 (†) <5 (†) <5 (†) 0 (0.0) 23 (1.9)
Trisomy 18 26 (3.1) <5 (†) 6 (2.7) <5 (†) 0 (0.0) 39 (3.2)
Trisomy 21 (Down syndrome) 137 (16.5) 14 (17.6) 59 (26.6) 8 (18.3) 8 (57.4) 233 (18.9)
Turner syndrome 15 (3.7) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 18 (3.0) 2
Ventricular septal defect 519 (62.3) 48 (60.4) 146 (65.9) 19 (43.4) 6 (43.1) 777 (62.9)
Total live births 83246 7946 22141 4376 1393 123488 3
Male Live Births 42433 4065 11347 2273 706 63093
Female Live Births 40811 3881 10794 2103 687 60393
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Nebraska
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 48 (4.6) <5 (†) 51 (4.1)
Trisomy 13 15 (1.4) 8 (4.0) 23 (1.9)
Trisomy 18 26 (2.5) 13 (6.6) 39 (3.2)
Trisomy 21 (Down syndrome) 124 (12.0) 109 (55.0) 233 (18.9)
Total live births 103668 19819 123488
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age