New York
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 21 (0.4) 5 (0.3) 14 (0.6) 0 (0.0) 0 (0.0) 42 (0.4)
Anophthalmia / microphthalmia 8 (0.6) <5 (†) 5 (0.5) <5 (†) 0 (0.0) 36 (1.1)
Anotia / microtia 12 (0.9) <5 (†) 16 (1.7) <5 (†) 0 (0.0) 47 (1.5)
Aortic valve stenosis 83 (1.6) 19 (1.3) 38 (1.6) 12 (1.1) 0 (0.0) 161 (1.5)
Atrial septal defect 6997 (132.6) 4050 (273.9) 4800 (196.1) 1748 (160.2) 25 (140.7) 18311 (171.1)
Atrioventricular septal defect (endocardial cushion defect) 249 (4.7) 145 (9.8) 216 (8.8) 43 (3.9) <5 (†) 685 (6.4)
Biliary atresia 80 (1.5) 91 (6.2) 83 (3.4) 31 (2.8) 0 (0.0) 296 (2.8)
Bladder exstrophy 14 (0.3) <5 (†) <5 (†) <5 (†) 0 (0.0) 22 (0.2)
Choanal atresia 131 (2.5) 32 (2.2) 41 (1.7) 11 (1.0) 0 (0.0) 221 (2.1)
Cleft lip alone (without cleft palate) 35 (2.5) 5 (0.9) 21 (2.3) <5 (†) 0 (0.0) 87 (2.8)
Cleft lip with cleft palate 47 (3.3) 5 (0.9) 26 (2.8) <5 (†) <5 (†) 133 (4.2)
Cleft palate alone (without cleft lip) 53 (3.8) 12 (2.2) 29 (3.1) 8 (5.2) 0 (0.0) 178 (5.6)
Cloacal exstrophy <5 (†) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) <5 (†)
Clubfoot 950 (18.0) 312 (21.1) 507 (20.7) 161 (14.8) <5 (†) 2029 (19.0)
Coarctation of aorta 33 (2.3) 11 (2.1) 17 (1.8) <5 (†) 0 (0.0) 140 (4.4)
Common truncus (truncus arteriosus or TA) 5 (0.4) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 17 (0.5)
Congenital cataract 19 (1.7) <5 (†) 9 (1.2) <5 (†) 0 (0.0) 55 (2.2)
Congenital posterior urethral valves 73 (2.7) 33 (4.4) 38 (3.1) 14 (2.5) <5 (†) 170 (3.1) 1
Craniosynostosis 637 (12.1) 183 (12.4) 378 (15.4) 118 (10.8) <5 (†) 1362 (12.7)
Deletion 22q11.2 92 (1.7) 41 (2.8) 67 (2.7) 25 (2.3) 0 (0.0) 241 (2.3)
Dextro-Transposition of great arteries (d-TGA) 21 (1.5) 8 (1.5) 6 (0.7) <5 (†) 0 (0.0) 74 (2.3)
Diaphragmatic hernia 23 (1.6) 6 (1.1) 14 (1.5) <5 (†) 0 (0.0) 74 (2.3)
Double outlet right ventricle (DORV) 163 (3.1) 66 (4.5) 93 (3.8) 37 (3.4) <5 (†) 385 (3.6)
Ebstein anomaly 44 (0.8) 12 (0.8) 30 (1.2) 11 (1.0) 0 (0.0) 99 (0.9)
Encephalocele 38 (0.7) 17 (1.1) 30 (1.2) 8 (0.7) 0 (0.0) 99 (0.9)
Esophageal atresia / tracheoesophageal fistula 32 (2.3) 13 (2.4) 10 (1.1) <5 (†) <5 (†) 83 (2.6)
Gastroschisis 20 (1.4) 5 (0.9) 30 (3.3) 0 (0.0) 0 (0.0) 74 (2.3)
Holoprosencephaly <5 (†) <5 (†) <5 (†) <5 (†) 0 (0.0) 17 (0.5)
Hypoplastic left heart syndrome 17 (1.2) 7 (1.3) <5 (†) <5 (†) 0 (0.0) 60 (1.9)
Hypospadias 2975 (110.2) 707 (94.1) 889 (71.6) 410 (72.9) 5 (54.7) 5231 (95.8) 1
Interrupted aortic arch (IAA) 44 (0.8) 18 (1.2) 18 (0.7) 8 (0.7) 0 (0.0) 93 (0.9)
Limb deficiencies (reduction defects) 146 (2.8) 57 (3.9) 80 (3.3) 17 (1.6) <5 (†) 316 (3.0)
Omphalocele 73 (1.4) 55 (3.7) 61 (2.5) 17 (1.6) 0 (0.0) 221 (2.1)
Pulmonary valve atresia 8 (0.6) <5 (†) <5 (†) <5 (†) 0 (0.0) 32 (1.0)
Rectal and large intestinal atresia / stenosis 207 (3.9) 67 (4.5) 136 (5.6) 43 (3.9) <5 (†) 481 (4.5)
Renal agenesis / hypoplasia 448 (8.5) 137 (9.3) 193 (7.9) 52 (4.8) 0 (0.0) 862 (8.1)
Single ventricle 62 (1.2) 38 (2.6) 47 (1.9) 11 (1.0) 0 (0.0) 171 (1.6)
Small intestinal atresia / stenosis 210 (4.0) 80 (5.4) 123 (5.0) 45 (4.1) <5 (†) 474 (4.4)
Spina bifida without anencephaly 23 (1.6) <5 (†) 17 (1.8) <5 (†) 0 (0.0) 67 (2.1)
Tetralogy of Fallot (TOF) 26 (1.8) 19 (3.6) 18 (2.0) 6 (3.9) <5 (†) 149 (4.7)
Total anomalous pulmonary venous connection (TAPVC) 6 (0.4) <5 (†) 5 (0.5) 0 (0.0) 0 (0.0) 37 (1.2)
Tricuspid valve atresia and stenosis 7 (0.5) <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 18 (0.6)
Trisomy 13 35 (0.7) 12 (0.8) 13 (0.5) 6 (0.6) 0 (0.0) 72 (0.7)
Trisomy 18 45 (0.9) 42 (2.8) 46 (1.9) <5 (†) 0 (0.0) 140 (1.3)
Trisomy 21 (Down syndrome) 612 (11.6) 246 (16.6) 419 (17.1) 61 (5.6) <5 (†) 1418 (13.3)
Turner syndrome 71 (2.8) 25 (3.4) 49 (4.1) 16 (3.0) 0 (0.0) 164 (3.1) 2
Ventricular septal defect 3305 (62.6) 1003 (67.8) 1892 (77.3) 624 (57.2) 10 (56.3) 7104 (66.4)
Total live births 527788 147847 244733 109086 1777 1070019 3
Male Live Births 269986 75132 124218 56260 914 546300
Female Live Births 257802 72715 120515 52826 863 523719
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
New York
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 70 (2.9) <5 (†) 74 (2.3)
Trisomy 13 36 (0.5) 34 (1.2) 72 (0.7)
Trisomy 18 54 (0.7) 81 (2.9) 140 (1.3)
Trisomy 21 (Down syndrome) 531 (6.7) 823 (29.9) 1418 (13.3)
Total live births 241583 73823 315407
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age
New York
Notes on Specific Birth Defects
Defect Site Comment
Anencephaly passive surveillance, statewide
Spina bifida without anencephaly confirmed with medical record review, from 14 county sub region
Encephalocele passive surveillance, statewide
Anophthalmia / microphthalmia confirmed with medical record review, from 14 county sub region
Congenital cataract confirmed with medical record review, from 14 county sub region
Anotia / microtia confirmed with medical record review, from 14 county sub region
Common truncus (truncus arteriosus or TA) confirmed with medical record review, from 14 county sub region
Dextro-Transposition of great arteries (d-TGA) confirmed with medical record review, from 14 county sub region
Tetralogy of Fallot (TOF) confirmed with medical record review, from 14 county sub region
Ventricular septal defect passive surveillance, statewide
Atrial septal defect passive surveillance, statewide
Atrioventricular septal defect (endocardial cushion defect) passive surveillance, statewide
Pulmonary valve atresia confirmed with medical record review, from 14 county sub region
Tricuspid valve atresia and stenosis confirmed with medical record review, from 14 county sub region
Ebstein anomaly passive surveillance, statewide
Aortic valve stenosis passive surveillance, statewide
Hypoplastic left heart syndrome confirmed with medical record review, from 14 county sub region
Coarctation of aorta confirmed with medical record review, from 14 county sub region
Total anomalous pulmonary venous connection (TAPVC) confirmed with medical record review, from 14 county sub region
Cleft palate alone (without cleft lip) confirmed with medical record review, from 14 county sub region
Choanal atresia passive surveillance, statewide
Esophageal atresia / tracheoesophageal fistula confirmed with medical record review, from 14 county sub region
Rectal and large intestinal atresia / stenosis passive surveillance, statewide
Biliary atresia passive surveillance, statewide
Renal agenesis / hypoplasia passive surveillance, statewide
Bladder exstrophy passive surveillance, statewide
Gastroschisis confirmed with medical record review, from 14 county sub region
Omphalocele passive surveillance, statewide
Diaphragmatic hernia confirmed with medical record review, from 14 county sub region
Trisomy 13 passive surveillance, statewide
Trisomy 21 (Down syndrome) passive surveillance, statewide
Trisomy 18 passive surveillance, statewide
Hypospadias passive surveillance, statewide
Turner syndrome passive surveillance, statewide
Deletion 22q11.2 passive surveillance, statewide
Limb deficiencies (reduction defects) passive surveillance, statewide
Craniosynostosis passive surveillance, statewide
Clubfoot passive surveillance, statewide
Congenital posterior urethral valves passive surveillance, statewide
Cloacal exstrophy passive surveillance, statewide
Small intestinal atresia / stenosis passive surveillance, statewide
Cleft lip alone (without cleft palate) confirmed with medical record review, from 14 county sub region
Cleft lip with cleft palate confirmed with medical record review, from 14 county sub region
Single ventricle passive surveillance, statewide
Interrupted aortic arch (IAA) passive surveillance, statewide
Double outlet right ventricle (DORV) passive surveillance, statewide
Holoprosencephaly confirmed with medical record review, from 14 county sub region