Ohio
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 33 (0.7) 7 (0.7) <5 (†) <5 (†) 0 (0.0) 42 (0.6)
Anophthalmia / microphthalmia 102 (2.2) 25 (2.3) 9 (2.2) <5 (†) 0 (0.0) 147 (2.2)
Anotia / microtia 7 (0.1) <5 (†) 0 (0.0) <5 (†) 0 (0.0) 9 (0.1)
Aortic valve stenosis 135 (2.9) 12 (1.1) 10 (2.5) <5 (†) 0 (0.0) 164 (2.5)
Biliary atresia 103 (2.2) 60 (5.6) 7 (1.7) 5 (2.4) 0 (0.0) 182 (2.8)
Choanal atresia 130 (2.8) 23 (2.1) 9 (2.2) 0 (0.0) 0 (0.0) 166 (2.5)
Cleft lip alone (without cleft palate) 130 (2.8) 16 (1.5) 9 (2.2) 5 (2.4) 0 (0.0) 170 (2.6)
Cleft lip with cleft palate 321 (6.9) 50 (4.7) 29 (7.2) 19 (9.2) 0 (0.0) 441 (6.7)
Cleft palate alone (without cleft lip) 614 (13.1) 71 (6.6) 31 (7.7) 18 (8.7) <5 (†) 769 (11.7)
Clubfoot 386 (8.3) 71 (6.6) 31 (7.7) 9 (4.4) 0 (0.0) 524 (8.0)
Coarctation of aorta 370 (7.9) 67 (6.3) 21 (5.2) 13 (6.3) 0 (0.0) 492 (7.5)
Common truncus (truncus arteriosus or TA) 60 (1.3) 14 (1.3) 5 (1.2) <5 (†) 0 (0.0) 84 (1.3)
Congenital cataract 187 (4.0) 53 (5.0) 21 (5.2) 13 (6.3) 0 (0.0) 287 (4.4)
Deletion 22q11.2 117 (2.5) 16 (1.5) 5 (1.2) <5 (†) 0 (0.0) 146 (2.2)
Dextro-Transposition of great arteries (d-TGA) 171 (3.7) 36 (3.4) 10 (2.5) 8 (3.9) 0 (0.0) 237 (3.6)
Diaphragmatic hernia 250 (5.3) 62 (5.8) 18 (4.5) 9 (4.4) 0 (0.0) 357 (5.4)
Encephalocele 44 (0.9) 17 (1.6) 7 (1.7) <5 (†) 0 (0.0) 78 (1.2)
Esophageal atresia / tracheoesophageal fistula 144 (3.1) 35 (3.3) 13 (3.2) 8 (3.9) 0 (0.0) 209 (3.2)
Gastroschisis 204 (4.4) 35 (3.3) 11 (2.7) 0 (0.0) <5 (†) 264 (4.0)
Holoprosencephaly 48 (1.0) 11 (1.0) <5 (†) <5 (†) 0 (0.0) 67 (1.0)
Hypoplastic left heart syndrome 131 (2.8) 26 (2.4) 8 (2.0) <5 (†) 0 (0.0) 178 (2.7)
Omphalocele 93 (2.0) 43 (4.0) 7 (1.7) <5 (†) 0 (0.0) 152 (2.3)
Pulmonary valve atresia 47 (1.0) 10 (0.9) 8 (2.0) <5 (†) 0 (0.0) 69 (1.0)
Pulmonary valve atresia and stenosis 47 (1.0) 10 (0.9) 8 (2.0) <5 (†) 0 (0.0) 69 (1.0)
Rectal and large intestinal atresia / stenosis 209 (4.5) 61 (5.7) 21 (5.2) 14 (6.8) 0 (0.0) 321 (4.9)
Renal agenesis / hypoplasia 467 (10.0) 130 (12.1) 41 (10.2) 15 (7.3) <5 (†) 679 (10.3)
Spina bifida without anencephaly 220 (4.7) 27 (2.5) 18 (4.5) <5 (†) 0 (0.0) 278 (4.2)
Tetralogy of Fallot (TOF) 242 (5.2) 60 (5.6) 27 (6.7) 8 (3.9) 0 (0.0) 356 (5.4)
Total anomalous pulmonary venous connection (TAPVC) 48 (1.0) 17 (1.6) <5 (†) <5 (†) 0 (0.0) 76 (1.2)
Transposition of the great arteries (TGA) 182 (3.9) 36 (3.4) 10 (2.5) 8 (3.9) 0 (0.0) 249 (3.8)
Tricuspid valve atresia 33 (0.7) 6 (0.6) <5 (†) 0 (0.0) 0 (0.0) 43 (0.7)
Tricuspid valve atresia and stenosis 33 (0.7) 6 (0.6) <5 (†) 0 (0.0) 0 (0.0) 43 (0.7)
Trisomy 13 31 (0.7) 6 (0.6) 5 (1.2) <5 (†) 0 (0.0) 44 (0.7)
Trisomy 18 66 (1.4) 36 (3.4) 7 (1.7) <5 (†) 0 (0.0) 116 (1.8)
Trisomy 21 (Down syndrome) 616 (13.2) 156 (14.6) 83 (20.7) 23 (11.1) 0 (0.0) 908 (13.8)
Turner syndrome 117 (5.1) 16 (3.0) 10 (5.1) <5 (†) 0 (0.0) 150 (4.7) 1
Total live births 467697 107033 40122 20669 482 657350 2
Male Live Births Not Reported Not Reported Not Reported Not Reported Not Reported Not Reported
Female Live Births 228646 52625 19645 10081 218 321712
Notes
1- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
2- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Ohio
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 252 (4.5) 11 (1.1) 264 (4.0)
Trisomy 13 30 (0.5) 14 (1.4) 44 (0.7)
Trisomy 18 61 (1.1) 55 (5.5) 116 (1.8)
Trisomy 21 (Down syndrome) 493 (8.9) 414 (41.2) 908 (13.8)
Total live births 556962 100388 657350
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age