Oklahoma
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 33 (2.5) <5 (†) 10 (2.5) <5 (†) 9 (4.0) 56 (2.3)
Anophthalmia / microphthalmia 21 (1.6) 6 (3.1) 8 (2.0) <5 (†) 6 (2.7) 42 (1.7)
Anotia / microtia 26 (1.9) <5 (†) 21 (5.3) 6 (8.4) 10 (4.4) 68 (2.8)
Aortic valve stenosis 42 (3.1) <5 (†) 11 (2.8) <5 (†) 9 (4.0) 65 (2.7)
Atrial septal defect 245 (18.2) 39 (19.8) 66 (16.6) 10 (14.0) 52 (23.1) 412 (16.9)
Atrioventricular septal defect (endocardial cushion defect) 85 (6.3) 18 (9.2) 33 (8.3) 6 (8.4) 14 (6.2) 156 (6.4)
Biliary atresia 11 (0.8) <5 (†) <5 (†) <5 (†) <5 (†) 21 (0.9)
Bladder exstrophy <5 (†) <5 (†) <5 (†) 0 (0.0) <5 (†) 8 (0.3)
Choanal atresia 49 (3.6) <5 (†) 8 (2.0) <5 (†) 5 (2.2) 65 (2.7)
Cleft lip alone (without cleft palate) 52 (3.9) 8 (4.1) 16 (4.0) <5 (†) 7 (3.1) 85 (3.5)
Cleft lip with cleft palate 113 (8.4) 11 (5.6) 29 (7.3) 6 (8.4) 26 (11.5) 185 (7.6)
Cleft palate alone (without cleft lip) 113 (8.4) 9 (4.6) 19 (4.8) 7 (9.8) 30 (13.3) 179 (7.4)
Cloacal exstrophy <5 (†) <5 (†) 0 (0.0) 0 (0.0) <5 (†) 6 (0.2)
Clubfoot 276 (20.5) 43 (21.9) 71 (17.9) 14 (19.6) 46 (20.4) 451 (18.5)
Coarctation of aorta 107 (8.0) 14 (7.1) 21 (5.3) <5 (†) 18 (8.0) 164 (6.7)
Common truncus (truncus arteriosus or TA) 13 (1.0) <5 (†) <5 (†) <5 (†) <5 (†) 18 (0.7)
Congenital cataract 29 (2.2) <5 (†) <5 (†) 0 (0.0) 7 (3.1) 44 (1.8)
Congenital posterior urethral valves 15 (2.2) 5 (5.0) <5 (†) <5 (†) 5 (4.3) 31 (2.5) 1
Craniosynostosis 115 (8.5) 13 (6.6) 21 (5.3) <5 (†) 22 (9.8) 175 (7.2)
Deletion 22q11.2 16 (1.2) 6 (3.1) 9 (2.3) 0 (0.0) <5 (†) 32 (1.3)
Dextro-Transposition of great arteries (d-TGA) 47 (3.5) <5 (†) 11 (2.8) <5 (†) 9 (4.0) 72 (3.0)
Diaphragmatic hernia 45 (3.3) 10 (5.1) 18 (4.5) 8 (11.2) 14 (6.2) 95 (3.9)
Double outlet right ventricle (DORV) 41 (3.0) 9 (4.6) 16 (4.0) <5 (†) 8 (3.6) 78 (3.2)
Ebstein anomaly 12 (0.9) <5 (†) <5 (†) <5 (†) <5 (†) 21 (0.9)
Encephalocele 19 (1.4) <5 (†) <5 (†) <5 (†) <5 (†) 27 (1.1)
Esophageal atresia / tracheoesophageal fistula 41 (3.0) <5 (†) 7 (1.8) <5 (†) 11 (4.9) 62 (2.5)
Gastroschisis 78 (5.8) 10 (5.1) 20 (5.0) 0 (0.0) 11 (4.9) 119 (4.9)
Holoprosencephaly 17 (1.3) 7 (3.6) 6 (1.5) 0 (0.0) <5 (†) 33 (1.4)
Hypoplastic left heart syndrome 48 (3.6) 5 (2.5) 6 (1.5) <5 (†) 6 (2.7) 67 (2.8)
Hypospadias 431 (62.6) 79 (78.6) 66 (32.4) 18 (48.6) 91 (78.8) 685 (55.0) 1
Interrupted aortic arch (IAA) 12 (0.9) <5 (†) <5 (†) <5 (†) <5 (†) 19 (0.8)
Limb deficiencies (reduction defects) 86 (6.4) 19 (9.7) 12 (3.0) 5 (7.0) 22 (9.8) 144 (5.9)
Omphalocele 36 (2.7) 12 (6.1) 5 (1.3) 0 (0.0) 8 (3.6) 61 (2.5)
Pulmonary valve atresia 39 (2.9) 5 (2.5) 11 (2.8) <5 (†) 5 (2.2) 61 (2.5)
Pulmonary valve atresia and stenosis 128 (9.5) 26 (13.2) 39 (9.8) <5 (†) 27 (12.0) 222 (9.1)
Rectal and large intestinal atresia / stenosis 92 (6.8) 10 (5.1) 31 (7.8) 6 (8.4) 25 (11.1) 164 (6.7)
Renal agenesis / hypoplasia 131 (9.7) 15 (7.6) 30 (7.6) 5 (7.0) 33 (14.6) 214 (8.8)
Single ventricle 7 (0.5) <5 (†) <5 (†) <5 (†) <5 (†) 12 (0.5)
Small intestinal atresia / stenosis 40 (3.0) 9 (4.6) 17 (4.3) <5 (†) 15 (6.7) 83 (3.4)
Spina bifida without anencephaly 60 (4.5) <5 (†) 15 (3.8) <5 (†) 7 (3.1) 90 (3.7)
Tetralogy of Fallot (TOF) 63 (4.7) 7 (3.6) 21 (5.3) <5 (†) 10 (4.4) 107 (4.4)
Total anomalous pulmonary venous connection (TAPVC) 18 (1.3) <5 (†) 9 (2.3) <5 (†) 5 (2.2) 39 (1.6)
Transposition of the great arteries (TGA) 53 (3.9) <5 (†) 12 (3.0) <5 (†) 10 (4.4) 80 (3.3)
Tricuspid valve atresia 13 (1.0) <5 (†) <5 (†) 0 (0.0) <5 (†) 20 (0.8)
Tricuspid valve atresia and stenosis 22 (1.6) 6 (3.1) 8 (2.0) <5 (†) 5 (2.2) 42 (1.7)
Trisomy 13 10 (0.7) <5 (†) 7 (1.8) <5 (†) <5 (†) 24 (1.0)
Trisomy 18 34 (2.5) 11 (5.6) 17 (4.3) <5 (†) <5 (†) 69 (2.8)
Trisomy 21 (Down syndrome) 176 (13.1) 23 (11.7) 72 (18.1) 12 (16.8) 32 (14.2) 316 (13.0)
Turner syndrome 18 (2.7) <5 (†) 6 (3.1) 0 (0.0) 6 (5.5) 35 (2.9) 2
Ventricular septal defect 765 (56.9) 134 (68.1) 251 (63.2) 51 (71.3) 191 (84.8) 1394 (57.3)
Total live births 134509 19666 39703 7148 22535 243287 3
Male Live Births 68828 10053 20351 3701 11550 124618
Female Live Births 65680 9613 19351 2916 10985 118667
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Oklahoma
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 116 (5.4) <5 (†) 119 (4.9)
Trisomy 13 17 (0.8) 7 (2.3) 24 (1.0)
Trisomy 18 33 (1.5) 36 (11.9) 69 (2.8)
Trisomy 21 (Down syndrome) 158 (7.4) 158 (52.2) 316 (13.0)
Total live births 212967 30260 243287
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age
Oklahoma
Notes on Specific Birth Defects
Defect Site Comment
Universal comment Denominator data obtained from OK2SHARE. OK2SHARE data is intended to support evidence-based decision making for public health in Oklahoma, to plan and improve service delivery, evaluate health care systems, inform policy decisions, and aid in research. Other uses or disclosures are not permitted. The purpose of the interactive Oklahoma State Department of Health (OSDH) OK2SHARE Service databases is to support the information needs of the Oklahoma State Department of Health and other users such as health officials, educators, and students in improving service delivery, evaluating health care systems, and monitoring the health of the people of Oklahoma. These databases may be used only for the purpose for which they are provided and may not be used in any way that would violate the HIPAA Privacy Rule External Link. Any effort to determine the identity of any reported cases, or to use the information for any purpose other than for statistical reporting and analysis, is prohibited.