| South Carolina Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
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| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
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| Anencephaly | 29 (1.8) | 11 (1.4) | 6 (2.0) | 0 (0.0) | 0 (0.0) | 46 (1.6) | |
| Anophthalmia / microphthalmia | 23 (1.4) | 13 (1.6) | <5 (†) | <5 (†) | 0 (0.0) | 41 (1.4) | |
| Anotia / microtia | 41 (2.5) | 7 (0.9) | 21 (7.1) | 0 (0.0) | 0 (0.0) | 70 (2.5) | |
| Aortic valve stenosis | 30 (1.8) | 10 (1.2) | 5 (1.7) | 0 (0.0) | 0 (0.0) | 45 (1.6) | |
| Atrial septal defect | 270 (16.4) | 146 (17.9) | 55 (18.7) | <5 (†) | <5 (†) | 477 (16.8) | |
| Atrioventricular septal defect (endocardial cushion defect) | 70 (4.2) | 48 (5.9) | 11 (3.7) | <5 (†) | 0 (0.0) | 132 (4.6) | |
| Biliary atresia | 9 (0.5) | 7 (0.9) | <5 (†) | <5 (†) | 0 (0.0) | 22 (0.8) | |
| Bladder exstrophy | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 0 (0.0) | <5 (†) | |
| Choanal atresia | 15 (0.9) | 9 (1.1) | <5 (†) | 0 (0.0) | 0 (0.0) | 28 (1.0) | |
| Cleft lip alone (without cleft palate) | 59 (3.6) | 9 (1.1) | 7 (2.4) | <5 (†) | 0 (0.0) | 76 (2.7) | |
| Cleft lip with cleft palate | 115 (7.0) | 45 (5.5) | 25 (8.5) | <5 (†) | <5 (†) | 191 (6.7) | |
| Cleft palate alone (without cleft lip) | 157 (9.5) | 53 (6.5) | 21 (7.1) | <5 (†) | <5 (†) | 238 (8.4) | |
| Coarctation of aorta | 94 (5.7) | 29 (3.6) | 15 (5.1) | <5 (†) | <5 (†) | 141 (5.0) | |
| Common truncus (truncus arteriosus or TA) | 16 (1.0) | 5 (0.6) | <5 (†) | 0 (0.0) | 0 (0.0) | 22 (0.8) | |
| Congenital cataract | 24 (1.5) | 25 (3.1) | 6 (2.0) | 0 (0.0) | 0 (0.0) | 56 (2.0) | |
| Congenital posterior urethral valves | 20 (2.4) | 19 (4.6) | <5 (†) | 0 (0.0) | <5 (†) | 43 (3.0) | 1 |
| Craniosynostosis | 152 (9.2) | 28 (3.4) | 18 (6.1) | <5 (†) | <5 (†) | 204 (7.2) | |
| Deletion 22q11.2 | 8 (0.5) | 10 (1.2) | <5 (†) | <5 (†) | 0 (0.0) | 22 (0.8) | |
| Diaphragmatic hernia | 65 (3.9) | 30 (3.7) | 7 (2.4) | <5 (†) | <5 (†) | 105 (3.7) | |
| Double outlet right ventricle (DORV) | 31 (1.9) | 37 (4.5) | 12 (4.1) | <5 (†) | 0 (0.0) | 82 (2.9) | |
| Ebstein anomaly | <5 (†) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 9 (0.3) | |
| Encephalocele | 10 (0.6) | 18 (2.2) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 29 (1.0) | |
| Esophageal atresia / tracheoesophageal fistula | 32 (1.9) | 10 (1.2) | 8 (2.7) | 0 (0.0) | 0 (0.0) | 50 (1.8) | |
| Gastroschisis | 49 (3.0) | 30 (3.7) | 17 (5.8) | 0 (0.0) | 0 (0.0) | 96 (3.4) | |
| Holoprosencephaly | 14 (0.8) | 12 (1.5) | <5 (†) | 0 (0.0) | 0 (0.0) | 31 (1.1) | |
| Hypoplastic left heart syndrome | 59 (3.6) | 24 (2.9) | 12 (4.1) | <5 (†) | 0 (0.0) | 97 (3.4) | |
| Hypospadias | 37 (4.4) | 23 (5.6) | <5 (†) | 0 (0.0) | 0 (0.0) | 61 (4.2) | 1 |
| Interrupted aortic arch (IAA) | 121 (7.3) | 45 (5.5) | 19 (6.4) | <5 (†) | <5 (†) | 188 (6.6) | |
| Limb deficiencies (reduction defects) | 89 (5.4) | 42 (5.2) | 26 (8.8) | 0 (0.0) | 0 (0.0) | 158 (5.6) | |
| Omphalocele | 44 (2.7) | 27 (3.3) | <5 (†) | <5 (†) | 0 (0.0) | 75 (2.6) | |
| Pulmonary valve atresia | 10 (0.6) | 10 (1.2) | <5 (†) | 0 (0.0) | <5 (†) | 25 (0.9) | |
| Pulmonary valve atresia and stenosis | 122 (7.4) | 86 (10.6) | 29 (9.8) | 5 (8.2) | <5 (†) | 250 (8.8) | |
| Rectal and large intestinal atresia / stenosis | 59 (3.6) | 33 (4.1) | 12 (4.1) | 0 (0.0) | <5 (†) | 106 (3.7) | |
| Renal agenesis / hypoplasia | 115 (7.0) | 53 (6.5) | 15 (5.1) | <5 (†) | 0 (0.0) | 188 (6.6) | |
| Single ventricle | 13 (0.8) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 17 (0.6) | |
| Small intestinal atresia / stenosis | 69 (4.2) | 37 (4.5) | 16 (5.4) | <5 (†) | <5 (†) | 124 (4.4) | |
| Spina bifida without anencephaly | 56 (3.4) | 22 (2.7) | 13 (4.4) | 0 (0.0) | 0 (0.0) | 92 (3.2) | |
| Tetralogy of Fallot (TOF) | 75 (4.5) | 36 (4.4) | 14 (4.7) | <5 (†) | 0 (0.0) | 129 (4.5) | |
| Total anomalous pulmonary venous connection (TAPVC) | 14 (0.8) | 7 (0.9) | 9 (3.1) | 0 (0.0) | 0 (0.0) | 30 (1.1) | |
| Transposition of the great arteries (TGA) | 44 (2.7) | 12 (1.5) | 10 (3.4) | 0 (0.0) | 0 (0.0) | 66 (2.3) | |
| Tricuspid valve atresia and stenosis | <5 (†) | 6 (0.7) | 6 (2.0) | 0 (0.0) | <5 (†) | 17 (0.6) | |
| Trisomy 13 | 27 (1.6) | 9 (1.1) | <5 (†) | 0 (0.0) | 0 (0.0) | 41 (1.4) | |
| Trisomy 18 | 46 (2.8) | 30 (3.7) | 10 (3.4) | <5 (†) | 0 (0.0) | 88 (3.1) | |
| Trisomy 21 (Down syndrome) | 211 (12.8) | 91 (11.2) | 68 (23.1) | 7 (11.4) | <5 (†) | 381 (13.4) | |
| Turner syndrome | 35 (4.4) | 10 (2.5) | 9 (6.1) | 0 (0.0) | <5 (†) | 55 (4.0) | 2 |
| Ventricular septal defect | 776 (47.0) | 393 (48.2) | 221 (74.9) | 29 (47.3) | 11 (185.5) | 1439 (50.6) | |
| Total live births | 165007 | 81457 | 29487 | 6128 | 593 | 284433 | 3 |
| Male Live Births | 84714 | 41269 | 14843 | 3179 | 304 | 145212 | |
| Female Live Births | 80293 | 40188 | 14644 | 2949 | 289 | 139221 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
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| South Carolina Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 94 (3.9) | <5 (†) | 96 (3.4) |
| Trisomy 13 | 25 (1.0) | 15 (3.4) | 41 (1.4) |
| Trisomy 18 | 42 (1.7) | 45 (10.1) | 88 (3.1) |
| Trisomy 21 (Down syndrome) | 178 (7.4) | 198 (44.6) | 381 (13.4) |
| Total live births | 240076 | 44351 | 284433 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
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