| Tennessee Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||||||
| Defect |
Maternal Race/Ethnicity
|
Total * | Notes | ||||
|---|---|---|---|---|---|---|---|
| White, Non-Hispanic |
Black, Non-Hispanic |
Hispanic, Non-Hispanic |
Asian or Pacific Islander, Non-Hispanic |
American Indian or Alaskan Native, Non-Hispanic |
|||
| Anencephaly | 32 (1.2) | 8 (1.0) | 7 (1.5) | <5 (†) | 0 (0.0) | 52 (1.3) | |
| Anophthalmia / microphthalmia | 32 (1.2) | 15 (2.0) | 8 (1.8) | <5 (†) | 0 (0.0) | 59 (1.5) | |
| Anotia / microtia | 57 (2.2) | 11 (1.4) | 17 (3.7) | <5 (†) | 0 (0.0) | 95 (2.4) | |
| Aortic valve stenosis | 56 (2.1) | 8 (1.0) | 9 (2.0) | <5 (†) | 0 (0.0) | 78 (1.9) | |
| Atrial septal defect | 5708 (218.9) | 2541 (332.0) | 901 (197.8) | 168 (178.7) | 6 (149.6) | 9536 (236.1) | |
| Atrioventricular septal defect (endocardial cushion defect) | 149 (5.7) | 75 (9.8) | 21 (4.6) | 5 (5.3) | 0 (0.0) | 255 (6.3) | |
| Biliary atresia | 94 (3.6) | 46 (6.0) | 18 (4.0) | 7 (7.4) | 0 (0.0) | 167 (4.1) | |
| Bladder exstrophy | 8 (0.3) | <5 (†) | <5 (†) | 0 (0.0) | 0 (0.0) | 12 (0.3) | |
| Choanal atresia | 58 (2.2) | 19 (2.5) | 14 (3.1) | <5 (†) | 0 (0.0) | 94 (2.3) | |
| Cleft lip alone (without cleft palate) | 96 (3.7) | 14 (1.8) | 14 (3.1) | <5 (†) | 0 (0.0) | 130 (3.2) | |
| Cleft lip with cleft palate | 234 (9.0) | 34 (4.4) | 47 (10.3) | 5 (5.3) | 0 (0.0) | 328 (8.1) | |
| Cleft palate alone (without cleft lip) | 265 (10.2) | 36 (4.7) | 34 (7.5) | 7 (7.4) | <5 (†) | 357 (8.8) | |
| Cloacal exstrophy | 6 (0.2) | 0 (0.0) | <5 (†) | 0 (0.0) | 0 (0.0) | 8 (0.2) | |
| Clubfoot | 693 (26.6) | 200 (26.1) | 105 (23.0) | 14 (14.9) | <5 (†) | 1043 (25.8) | |
| Coarctation of aorta | 222 (8.5) | 46 (6.0) | 36 (7.9) | <5 (†) | 0 (0.0) | 315 (7.8) | |
| Common truncus (truncus arteriosus or TA) | 20 (0.8) | 5 (0.7) | 6 (1.3) | <5 (†) | 0 (0.0) | 34 (0.8) | |
| Congenital cataract | 65 (2.5) | 20 (2.6) | 7 (1.5) | 0 (0.0) | 0 (0.0) | 93 (2.3) | |
| Congenital posterior urethral valves | 35 (2.6) | 15 (3.9) | <5 (†) | <5 (†) | 0 (0.0) | 57 (2.8) | 1 |
| Craniosynostosis | 518 (19.9) | 55 (7.2) | 62 (13.6) | 12 (12.8) | <5 (†) | 657 (16.3) | |
| Deletion 22q11.2 | 31 (1.2) | 7 (0.9) | <5 (†) | <5 (†) | 0 (0.0) | 41 (1.0) | |
| Dextro-Transposition of great arteries (d-TGA) | 101 (3.9) | 21 (2.7) | 14 (3.1) | <5 (†) | 0 (0.0) | 140 (3.5) | |
| Diaphragmatic hernia | 95 (3.6) | 33 (4.3) | 17 (3.7) | <5 (†) | 0 (0.0) | 157 (3.9) | |
| Double outlet right ventricle (DORV) | 84 (3.2) | 31 (4.1) | 16 (3.5) | <5 (†) | 0 (0.0) | 137 (3.4) | |
| Ebstein anomaly | 44 (1.7) | 7 (0.9) | 7 (1.5) | 0 (0.0) | 0 (0.0) | 59 (1.5) | |
| Encephalocele | 37 (1.4) | 8 (1.0) | <5 (†) | <5 (†) | 0 (0.0) | 52 (1.3) | |
| Esophageal atresia / tracheoesophageal fistula | 94 (3.6) | 15 (2.0) | 16 (3.5) | <5 (†) | 0 (0.0) | 129 (3.2) | |
| Gastroschisis | 121 (4.6) | 25 (3.3) | 20 (4.4) | <5 (†) | <5 (†) | 174 (4.3) | |
| Holoprosencephaly | 29 (1.1) | 17 (2.2) | 14 (3.1) | <5 (†) | 0 (0.0) | 65 (1.6) | |
| Hypoplastic left heart syndrome | 114 (4.4) | 37 (4.8) | 8 (1.8) | <5 (†) | 0 (0.0) | 165 (4.1) | |
| Hypospadias | 1622 (121.7) | 401 (103.6) | 120 (51.6) | 36 (75.2) | <5 (†) | 2243 (108.9) | 1 |
| Interrupted aortic arch (IAA) | 23 (0.9) | 12 (1.6) | <5 (†) | 0 (0.0) | 0 (0.0) | 41 (1.0) | |
| Limb deficiencies (reduction defects) | 94 (3.6) | 28 (3.7) | 22 (4.8) | <5 (†) | 0 (0.0) | 149 (3.7) | |
| Omphalocele | 77 (3.0) | 24 (3.1) | 11 (2.4) | <5 (†) | 0 (0.0) | 115 (2.8) | |
| Pulmonary valve atresia | 47 (1.8) | 12 (1.6) | 9 (2.0) | <5 (†) | 0 (0.0) | 75 (1.9) | |
| Pulmonary valve atresia and stenosis | 234 (9.0) | 108 (14.1) | 39 (8.6) | <5 (†) | 0 (0.0) | 395 (9.8) | |
| Rectal and large intestinal atresia / stenosis | 136 (5.2) | 40 (5.2) | 33 (7.2) | 5 (5.3) | 0 (0.0) | 220 (5.4) | |
| Renal agenesis / hypoplasia | 220 (8.4) | 50 (6.5) | 38 (8.3) | <5 (†) | 0 (0.0) | 323 (8.0) | |
| Single ventricle | 57 (2.2) | 12 (1.6) | 10 (2.2) | <5 (†) | 0 (0.0) | 84 (2.1) | |
| Small intestinal atresia / stenosis | 95 (3.6) | 25 (3.3) | 21 (4.6) | <5 (†) | 0 (0.0) | 146 (3.6) | |
| Spina bifida without anencephaly | 123 (4.7) | 18 (2.4) | 20 (4.4) | <5 (†) | 0 (0.0) | 164 (4.1) | |
| Tetralogy of Fallot (TOF) | 161 (6.2) | 46 (6.0) | 21 (4.6) | <5 (†) | 0 (0.0) | 242 (6.0) | |
| Total anomalous pulmonary venous connection (TAPVC) | 33 (1.3) | <5 (†) | 10 (2.2) | 0 (0.0) | 0 (0.0) | 48 (1.2) | |
| Transposition of the great arteries (TGA) | 105 (4.0) | 24 (3.1) | 15 (3.3) | <5 (†) | <5 (†) | 150 (3.7) | |
| Tricuspid valve atresia | 28 (1.1) | 8 (1.0) | 7 (1.5) | <5 (†) | 0 (0.0) | 47 (1.2) | |
| Tricuspid valve atresia and stenosis | 28 (1.1) | 8 (1.0) | 7 (1.5) | <5 (†) | 0 (0.0) | 47 (1.2) | |
| Trisomy 13 | 28 (1.1) | 9 (1.2) | <5 (†) | 0 (0.0) | 0 (0.0) | 41 (1.0) | |
| Trisomy 18 | 50 (1.9) | 20 (2.6) | 18 (4.0) | <5 (†) | 0 (0.0) | 92 (2.3) | |
| Trisomy 21 (Down syndrome) | 375 (14.4) | 100 (13.1) | 111 (24.4) | 9 (9.6) | 0 (0.0) | 607 (15.0) | |
| Turner syndrome | 51 (4.0) | 9 (2.4) | 7 (3.1) | <5 (†) | 0 (0.0) | 71 (3.6) | 2 |
| Ventricular septal defect | 1572 (60.3) | 492 (64.3) | 323 (70.9) | 40 (42.6) | <5 (†) | 2492 (61.7) | |
| Total live births | 260781 | 76534 | 45559 | 9399 | 401 | 403830 | 3 |
| Male Live Births | 133328 | 38714 | 23266 | 4787 | 199 | 205912 | |
| Female Live Births | 127448 | 37815 | 22291 | 4612 | 202 | 197906 | |
| Notes 1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births. 2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births. 3- Data for total live births include unknown infant sex. General comments †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other race |
|||||||
| Tennessee Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births) |
|||
| Defect |
Maternal Age
|
Total * | |
|---|---|---|---|
| Less than 35 years | 35 of more years | ||
| Gastroschisis | 164 (4.7) | 10 (1.7) | 174 (4.3) |
| Trisomy 13 | 32 (0.9) | 9 (1.6) | 41 (1.0) |
| Trisomy 18 | 39 (1.1) | 53 (9.2) | 92 (2.3) |
| Trisomy 21 (Down syndrome) | 307 (8.9) | 300 (52.0) | 607 (15.0) |
| Total live births | 346035 | 57731 | 403830 |
| Notes †- Counts <5 and associated prevalences are suppressed *- Data for totals include unknown/other maternal age |
|||
| Tennessee Notes on Specific Birth Defects |
|
| Defect | Site Comment |
|---|---|
| Anencephaly | Anencephalus is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Spina bifida without anencephaly | Spina bifida is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Anophthalmia / microphthalmia | Anophthalmia/microphthalmia is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Common truncus (truncus arteriosus or TA) | Common truncus is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Transposition of the great arteries (TGA) | Transposition of great arteries is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Dextro-Transposition of great arteries (d-TGA) | Dextro-transposition of great arteries is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Tetralogy of Fallot (TOF) | Tetralogy of Fallot is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Atrioventricular septal defect (endocardial cushion defect) | Atrioventricular septal defect is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Pulmonary valve atresia | Pulmonary valve atresia is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Tricuspid valve atresia | Tricuspid valve atresia is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Ebstein anomaly | Ebstein's anomaly is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Hypoplastic left heart syndrome | Hypoplastic left heart syndrome is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Coarctation of aorta | Coarctation of aorta is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Total anomalous pulmonary venous connection (TAPVC) | Total anomalous pulmonary venous connection is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Cleft palate alone (without cleft lip) | Cleft palate alone is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Esophageal atresia / tracheoesophageal fistula | Esophageal atresia/tracheoesophageal fistula is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Gastroschisis | Gastroschisis is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Omphalocele | Omphalocele is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Diaphragmatic hernia | Diaphragmatic hernia is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Trisomy 21 (Down syndrome) | Trisomy 21 is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Limb deficiencies (reduction defects) | Limb deficiencies is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Small intestinal atresia / stenosis | Small intestinal atresia/stenosis is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Cleft lip alone (without cleft palate) | Cleft lip alone is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Cleft lip with cleft palate | Cleft lip with cleft palate is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Single ventricle | Single ventricle is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Interrupted aortic arch (IAA) | Interrupted aortic arch is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Double outlet right ventricle (DORV) | Double outlet right ventricle is one of 27 conditions TN performs diagnosis verification (through medical record review) for. This review is complete for birth years 2018-2020 and currently incomplete for birth years 2021-2023. Because of this, counts may appear higher for birth years 2021-2023 as false positives (i.e. inaccurately reported cases) have not yet been removed as they have for the earlier birth years. |
| Universal comment | Note that male and female live birth numbers do not sum to overall live birth total due to a small number of live births each year that had unknown sex. |