Texas
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 111 (1.8) 35 (1.5) 219 (2.4) 17 (1.7) 0 (0.0) 403 (2.1)
Anophthalmia / microphthalmia 167 (2.8) 48 (2.1) 302 (3.3) 21 (2.1) 0 (0.0) 553 (2.9)
Anotia / microtia 200 (3.3) 46 (2.0) 575 (6.4) 44 (4.4) 0 (0.0) 880 (4.7)
Aortic valve stenosis 183 (3.0) 40 (1.7) 233 (2.6) 22 (2.2) <5 (†) 485 (2.6)
Atrial septal defect 5079 (84.0) 2393 (103.1) 9816 (108.8) 608 (60.8) 31 (94.1) 18240 (96.7)
Atrioventricular septal defect (endocardial cushion defect) 354 (5.9) 176 (7.6) 472 (5.2) 32 (3.2) <5 (†) 1055 (5.6)
Biliary atresia 26 (0.4) 24 (1.0) 54 (0.6) 9 (0.9) 0 (0.0) 119 (0.6)
Bladder exstrophy 15 (0.2) 7 (0.3) 8 (0.1) <5 (†) 0 (0.0) 35 (0.2)
Choanal atresia 94 (1.6) 33 (1.4) 125 (1.4) 8 (0.8) <5 (†) 265 (1.4)
Cleft lip alone (without cleft palate) 240 (4.0) 80 (3.4) 285 (3.2) 34 (3.4) 0 (0.0) 657 (3.5)
Cleft lip with cleft palate 413 (6.8) 90 (3.9) 778 (8.6) 49 (4.9) 5 (15.2) 1370 (7.3)
Cleft palate alone (without cleft lip) 407 (6.7) 106 (4.6) 522 (5.8) 59 (5.9) 5 (15.2) 1137 (6.0)
Cloacal exstrophy 7 (0.1) 5 (0.2) 8 (0.1) <5 (†) 0 (0.0) 21 (0.1)
Clubfoot 1197 (19.8) 496 (21.4) 1844 (20.4) 148 (14.8) 8 (24.3) 3784 (20.1)
Coarctation of aorta 377 (6.2) 95 (4.1) 578 (6.4) 33 (3.3) <5 (†) 1100 (5.8)
Common truncus (truncus arteriosus or TA) 32 (0.5) 15 (0.6) 72 (0.8) <5 (†) 0 (0.0) 128 (0.7)
Congenital cataract 128 (2.1) 64 (2.8) 200 (2.2) 24 (2.4) <5 (†) 421 (2.2)
Congenital posterior urethral valves 73 (2.4) 54 (4.6) 77 (1.7) 15 (2.9) 0 (0.0) 226 (2.3) 1
Craniosynostosis 536 (8.9) 84 (3.6) 677 (7.5) 42 (4.2) <5 (†) 1369 (7.3)
Deletion 22q11.2 77 (1.3) 36 (1.6) 132 (1.5) <5 (†) 0 (0.0) 253 (1.3)
Dextro-Transposition of great arteries (d-TGA) 156 (2.6) 39 (1.7) 210 (2.3) 23 (2.3) 0 (0.0) 441 (2.3)
Diaphragmatic hernia 187 (3.1) 66 (2.8) 301 (3.3) 26 (2.6) 0 (0.0) 588 (3.1)
Double outlet right ventricle (DORV) 148 (2.4) 86 (3.7) 284 (3.1) 20 (2.0) <5 (†) 550 (2.9)
Ebstein anomaly 62 (1.0) 10 (0.4) 88 (1.0) 10 (1.0) 0 (0.0) 173 (0.9)
Encephalocele 65 (1.1) 39 (1.7) 93 (1.0) <5 (†) <5 (†) 216 (1.1)
Esophageal atresia / tracheoesophageal fistula 165 (2.7) 48 (2.1) 189 (2.1) 17 (1.7) 0 (0.0) 430 (2.3)
Gastroschisis 256 (4.2) 68 (2.9) 466 (5.2) 12 (1.2) <5 (†) 827 (4.4)
Holoprosencephaly 49 (0.8) 23 (1.0) 102 (1.1) <5 (†) <5 (†) 183 (1.0)
Hypoplastic left heart syndrome 153 (2.5) 51 (2.2) 208 (2.3) 6 (0.6) <5 (†) 427 (2.3)
Hypospadias 2882 (92.8) 1009 (85.6) 2282 (49.6) 325 (63.0) 7 (41.1) 6654 (69.0) 1
Interrupted aortic arch (IAA) 41 (0.7) 18 (0.8) 69 (0.8) <5 (†) 0 (0.0) 134 (0.7)
Limb deficiencies (reduction defects) 295 (4.9) 162 (7.0) 529 (5.9) 31 (3.1) <5 (†) 1044 (5.5)
Omphalocele 142 (2.3) 69 (3.0) 193 (2.1) 14 (1.4) <5 (†) 434 (2.3)
Pulmonary valve atresia 41 (0.7) 24 (1.0) 76 (0.8) 9 (0.9) 0 (0.0) 151 (0.8)
Pulmonary valve atresia and stenosis 665 (11.0) 367 (15.8) 1131 (12.5) 77 (7.7) 7 (21.3) 2294 (12.2)
Rectal and large intestinal atresia / stenosis 299 (4.9) 112 (4.8) 560 (6.2) 44 (4.4) <5 (†) 1038 (5.5)
Renal agenesis / hypoplasia 515 (8.5) 202 (8.7) 792 (8.8) 70 (7.0) <5 (†) 1626 (8.6)
Single ventricle 49 (0.8) 15 (0.6) 75 (0.8) <5 (†) 0 (0.0) 144 (0.8)
Small intestinal atresia / stenosis 214 (3.5) 88 (3.8) 372 (4.1) 29 (2.9) <5 (†) 725 (3.8)
Spina bifida without anencephaly 198 (3.3) 54 (2.3) 390 (4.3) 22 (2.2) 0 (0.0) 681 (3.6)
Tetralogy of Fallot (TOF) 279 (4.6) 136 (5.9) 406 (4.5) 52 (5.2) <5 (†) 890 (4.7)
Total anomalous pulmonary venous connection (TAPVC) 75 (1.2) 26 (1.1) 198 (2.2) 9 (0.9) <5 (†) 311 (1.6)
Transposition of the great arteries (TGA) 209 (3.5) 45 (1.9) 269 (3.0) 30 (3.0) 0 (0.0) 568 (3.0)
Tricuspid valve atresia 38 (0.6) 17 (0.7) 73 (0.8) <5 (†) 0 (0.0) 132 (0.7)
Tricuspid valve atresia and stenosis 146 (2.4) 67 (2.9) 222 (2.5) 16 (1.6) <5 (†) 458 (2.4)
Trisomy 13 56 (0.9) 29 (1.2) 92 (1.0) <5 (†) <5 (†) 186 (1.0)
Trisomy 18 108 (1.8) 66 (2.8) 222 (2.5) 12 (1.2) 0 (0.0) 426 (2.3)
Trisomy 21 (Down syndrome) 737 (12.2) 318 (13.7) 1596 (17.7) 107 (10.7) 8 (24.3) 2824 (15.0)
Turner syndrome 104 (3.5) 35 (3.1) 130 (2.9) 11 (2.3) <5 (†) 293 (3.2) 2
Ventricular septal defect 3969 (65.6) 1413 (60.9) 7592 (84.2) 572 (57.2) 25 (75.9) 13828 (73.3)
Total live births 604578 232152 901907 100049 3293 1886045 3
Male Live Births 310621 117888 459728 51557 1703 964045
Female Live Births 293956 114260 442176 48491 1590 921990
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Texas
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 793 (5.0) 33 (1.0) 827 (4.4)
Trisomy 13 108 (0.7) 76 (2.4) 186 (1.0)
Trisomy 18 184 (1.2) 242 (7.7) 426 (2.3)
Trisomy 21 (Down syndrome) 1341 (8.5) 1483 (47.1) 2824 (15.0)
Total live births 1570959 315043 1886045
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age
Texas
Notes on Specific Birth Defects
Defect Site Comment
Tetralogy of Fallot (TOF) Includes any pulmonary valve atresia with co-occurring ventricular septal defect.
Ventricular septal defect Inlet VSD code was added in July 2019. Prior to July 2019, we are unable to distinguish inlet VSD from other types of VSD.
Pulmonary valve atresia Excludes pulmonary valve atresia with co-occurring ventricular septal defect or tetralogy of Fallot.
Choanal atresia May include stenosis.
Hypospadias Data for this condition include male and unknown gender cases only.
Turner syndrome Data for this condition include female and unknown gender cases only.
Congenital posterior urethral valves Data for this condition include male and unknown gender cases only.
Universal comment Texas only reports definite diagnoses for all defects reported. Possible/probable diagnoses are not included.
Universal comment Texas case definition includes livebirths, stillbirths, and terminations at any length of gestation and any birthweight.