Wisconsin
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Race/Ethnicity
Total * Notes
White,
Non-Hispanic
Black,
Non-Hispanic
Hispanic,
Non-Hispanic
Asian or
Pacific Islander,
Non-Hispanic
American Indian
or Alaskan Native,
Non-Hispanic
Anencephaly 30 (1.3) <5 (†) 8 (2.4) <5 (†) 0 (0.0) 44 (1.4)
Anophthalmia / microphthalmia 6 (0.3) <5 (†) <5 (†) <5 (†) 0 (0.0) 13 (0.4)
Anotia / microtia 29 (1.3) <5 (†) 6 (1.8) <5 (†) 0 (0.0) 42 (1.3)
Aortic valve stenosis 27 (1.2) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 31 (1.0)
Atrial septal defect 1560 (69.1) 282 (89.1) 202 (60.2) 82 (59.7) 40 (133.7) 2229 (70.2)
Atrioventricular septal defect (endocardial cushion defect) 75 (3.3) 11 (3.5) 13 (3.9) <5 (†) 0 (0.0) 105 (3.3)
Biliary atresia 7 (0.3) 6 (1.9) 6 (1.8) <5 (†) 0 (0.0) 24 (0.8)
Bladder exstrophy <5 (†) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 5 (0.2)
Choanal atresia 22 (1.0) <5 (†) <5 (†) <5 (†) 0 (0.0) 26 (0.8)
Cleft lip alone (without cleft palate) 67 (3.0) 7 (2.2) 10 (3.0) <5 (†) 0 (0.0) 91 (2.9)
Cleft lip with cleft palate 113 (5.0) 7 (2.2) 20 (6.0) 8 (5.8) <5 (†) 153 (4.8)
Cleft palate alone (without cleft lip) 103 (4.6) 8 (2.5) 13 (3.9) 8 (5.8) <5 (†) 133 (4.2)
Cloacal exstrophy <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 0 (0.0) <5 (†)
Clubfoot 363 (16.1) 51 (16.1) 57 (17.0) 22 (16.0) 7 (23.4) 515 (16.2)
Coarctation of aorta 88 (3.9) <5 (†) 12 (3.6) 8 (5.8) 0 (0.0) 117 (3.7)
Common truncus (truncus arteriosus or TA) 8 (0.4) <5 (†) <5 (†) <5 (†) 0 (0.0) 12 (0.4)
Congenital cataract 6 (0.3) <5 (†) 0 (0.0) 0 (0.0) 0 (0.0) 9 (0.3)
Congenital posterior urethral valves 12 (1.0) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 17 (1.0) 1
Craniosynostosis 58 (2.6) 0 (0.0) <5 (†) 0 (0.0) <5 (†) 63 (2.0)
Deletion 22q11.2 7 (0.3) 0 (0.0) <5 (†) <5 (†) 0 (0.0) 10 (0.3)
Dextro-Transposition of great arteries (d-TGA) 55 (2.4) <5 (†) <5 (†) <5 (†) <5 (†) 67 (2.1)
Diaphragmatic hernia 55 (2.4) 6 (1.9) 11 (3.3) <5 (†) 0 (0.0) 77 (2.4)
Double outlet right ventricle (DORV) 32 (1.4) <5 (†) 10 (3.0) <5 (†) 0 (0.0) 52 (1.6)
Ebstein anomaly 15 (0.7) 0 (0.0) <5 (†) 0 (0.0) <5 (†) 18 (0.6)
Encephalocele 9 (0.4) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 16 (0.5)
Esophageal atresia / tracheoesophageal fistula 39 (1.7) 5 (1.6) 5 (1.5) 0 (0.0) 0 (0.0) 53 (1.7)
Gastroschisis 61 (2.7) 16 (5.1) 16 (4.8) 5 (3.6) 0 (0.0) 102 (3.2)
Holoprosencephaly 11 (0.5) 0 (0.0) 0 (0.0) <5 (†) 0 (0.0) 14 (0.4)
Hypoplastic left heart syndrome 71 (3.1) 8 (2.5) 10 (3.0) <5 (†) <5 (†) 94 (3.0)
Hypospadias 726 (62.8) 108 (66.9) 53 (30.9) 17 (24.2) 6 (40.2) 941 (57.9) 1
Interrupted aortic arch (IAA) 183 (8.1) 39 (12.3) 33 (9.8) 8 (5.8) <5 (†) 275 (8.7)
Limb deficiencies (reduction defects) 59 (2.6) 10 (3.2) 9 (2.7) <5 (†) <5 (†) 88 (2.8)
Omphalocele 45 (2.0) <5 (†) 9 (2.7) <5 (†) <5 (†) 63 (2.0)
Pulmonary valve atresia 9 (0.4) 0 (0.0) <5 (†) 0 (0.0) 0 (0.0) 11 (0.3)
Pulmonary valve atresia and stenosis 89 (3.9) <5 (†) 17 (5.1) 5 (3.6) <5 (†) 120 (3.8)
Rectal and large intestinal atresia / stenosis 45 (2.0) <5 (†) <5 (†) <5 (†) 0 (0.0) 55 (1.7)
Renal agenesis / hypoplasia 135 (6.0) 16 (5.1) 23 (6.9) 7 (5.1) <5 (†) 191 (6.0)
Single ventricle 10 (0.4) <5 (†) <5 (†) <5 (†) 0 (0.0) 15 (0.5)
Small intestinal atresia / stenosis 41 (1.8) 9 (2.8) 6 (1.8) <5 (†) 0 (0.0) 60 (1.9)
Spina bifida without anencephaly 38 (1.7) <5 (†) 8 (2.4) 0 (0.0) 0 (0.0) 51 (1.6)
Tetralogy of Fallot (TOF) 64 (2.8) 11 (3.5) 7 (2.1) 5 (3.6) <5 (†) 96 (3.0)
Total anomalous pulmonary venous connection (TAPVC) 12 (0.5) <5 (†) <5 (†) <5 (†) 0 (0.0) 16 (0.5)
Transposition of the great arteries (TGA) 59 (2.6) <5 (†) <5 (†) <5 (†) <5 (†) 71 (2.2)
Tricuspid valve atresia 9 (0.4) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 12 (0.4)
Tricuspid valve atresia and stenosis 9 (0.4) <5 (†) <5 (†) 0 (0.0) 0 (0.0) 12 (0.4)
Trisomy 13 19 (0.8) <5 (†) <5 (†) <5 (†) 0 (0.0) 28 (0.9)
Trisomy 18 40 (1.8) 6 (1.9) 10 (3.0) 6 (4.4) 0 (0.0) 65 (2.0)
Trisomy 21 (Down syndrome) 235 (10.4) 30 (9.5) 60 (17.9) 10 (7.3) <5 (†) 342 (10.8)
Turner syndrome 21 (1.9) <5 (†) 8 (4.9) 0 (0.0) 0 (0.0) 33 (2.1) 2
Ventricular septal defect 993 (44.0) 126 (39.8) 147 (43.8) 45 (32.8) 18 (60.2) 1365 (43.0)
Total live births 225751 31652 33545 13737 2991 317309 3
Male Live Births 115670 16145 17145 7017 1492 162412
Female Live Births 110080 15506 16398 6719 1499 154892
Notes
1- Data for this condition include male and unknown infant sex cases only. Prevalence is calculated per 10,000 male live births.
2- Data for this condition include female and unknown infant sex cases only. Prevalence is calculated per 10,000 female live births.
3- Data for total live births include unknown infant sex.

General comments
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other race
Wisconsin
Birth Defects Counts and Prevalence 2018-2022 (Prevalence per 10,000 Live Births)
Defect
Maternal Age
Total *
Less than 35 years 35 of more years
Gastroschisis 96 (3.7) 6 (1.1) 102 (3.2)
Trisomy 13 18 (0.7) 10 (1.8) 28 (0.9)
Trisomy 18 33 (1.3) 32 (5.8) 65 (2.0)
Trisomy 21 (Down syndrome) 167 (6.4) 175 (31.8) 342 (10.8)
Total live births 262358 54951 317309
Notes
†- Counts <5 and associated prevalences are suppressed
*- Data for totals include unknown/other maternal age